Neurovascular Compression and Essential Hypertension — A Possible Link?

Abstract

Numerous observations, both experimental and clinical, demonstrate important role of vascular compression of the left rostral ventrolateral medulla in pathogenesis of essential hypertension. Hypertension caused by posterior fossa neurovascular anomaly, appears to be an attractive idea. Microvascular decompression may lower blood pressure in some patients. Article reviews data obtained from experimental studies, radiographic findings and clinical trials. Mechanisms through which vascular compression of brain stem can influence blood pressure level are discussed. Relevance of presented data in clinical practice is argued.