open access

Vol 6, No 3 (2002)
REVIEV
Published online: 2002-07-01
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Kidney and Sympathetic Nervous System in Hypertension

Witold Doroszewski, Beata Sulikowska, Jacek Manitius
Nadciśnienie tętnicze 2002;6(3):195-204.

open access

Vol 6, No 3 (2002)
REVIEV
Published online: 2002-07-01

Abstract

Nowdays in clinical investigations accented a very important influence of sympathetic overactivity in hypertension pathogenesis and progression of chronic renal failure.The correlation among renal function and sympathetic nerve system are difficult. On the one hand, the sympathetic nerve system affects renal function, i.e. renal hemodynamics flow, tubular sodium transport, renin secretion and activation of RAA system. On the other hand, the kidney is the source of activating afferent signals, presumably via stimulation of chemoreceptors and baroreceptors. The complicated mechanisms of blood pressure regulation and their correlation cause many functional and structural changes in organs and finally organs failure. Knowledge of these mechanisms give some therapeutic implications, help reduced blood pressure in hypertension patients and stopped development of functional and morphological changes in organs.

Abstract

Nowdays in clinical investigations accented a very important influence of sympathetic overactivity in hypertension pathogenesis and progression of chronic renal failure.The correlation among renal function and sympathetic nerve system are difficult. On the one hand, the sympathetic nerve system affects renal function, i.e. renal hemodynamics flow, tubular sodium transport, renin secretion and activation of RAA system. On the other hand, the kidney is the source of activating afferent signals, presumably via stimulation of chemoreceptors and baroreceptors. The complicated mechanisms of blood pressure regulation and their correlation cause many functional and structural changes in organs and finally organs failure. Knowledge of these mechanisms give some therapeutic implications, help reduced blood pressure in hypertension patients and stopped development of functional and morphological changes in organs.
Get Citation

Keywords

sympathetic nervous system overactivity; hypertension; chronic renal failure; imidazoline receptors

About this article
Title

Kidney and Sympathetic Nervous System in Hypertension

Journal

Arterial Hypertension

Issue

Vol 6, No 3 (2002)

Pages

195-204

Published online

2002-07-01

Bibliographic record

Nadciśnienie tętnicze 2002;6(3):195-204.

Keywords

sympathetic nervous system overactivity
hypertension
chronic renal failure
imidazoline receptors

Authors

Witold Doroszewski
Beata Sulikowska
Jacek Manitius

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