open access

Vol 7, No 4 (2003)
REVIEV
Published online: 2003-09-24
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Hypertension and a Function of Peroxisome Proliferator-Activated Receptor gamma

Małgorzata Gacka, Rajmund Adamiec
Nadciśnienie tętnicze 2003;7(4):281-285.

open access

Vol 7, No 4 (2003)
REVIEV
Published online: 2003-09-24

Abstract

Hypertension is one of the civilization’s disease. The coexistence of systemic metabolic disorders, especially insulin resistance, cause progression of hypertension and the risk of cardiovascular diseases in the course of atherosclerosis. This review will discuss the role of peroxisome proliferator-activated receptor gamma (PPARgamma) in hypertension. Thiazolidinediones, which are activators PPARgamma, could be a turning-point in the treatment of polymetabolic syndrome, because of reducing of insulin resistance and hypertension at the same time.

Abstract

Hypertension is one of the civilization’s disease. The coexistence of systemic metabolic disorders, especially insulin resistance, cause progression of hypertension and the risk of cardiovascular diseases in the course of atherosclerosis. This review will discuss the role of peroxisome proliferator-activated receptor gamma (PPARgamma) in hypertension. Thiazolidinediones, which are activators PPARgamma, could be a turning-point in the treatment of polymetabolic syndrome, because of reducing of insulin resistance and hypertension at the same time.
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Keywords

hypertension; insulin resistance; PPARgamma

About this article
Title

Hypertension and a Function of Peroxisome Proliferator-Activated Receptor gamma

Journal

Arterial Hypertension

Issue

Vol 7, No 4 (2003)

Pages

281-285

Published online

2003-09-24

Bibliographic record

Nadciśnienie tętnicze 2003;7(4):281-285.

Keywords

hypertension
insulin resistance
PPARgamma

Authors

Małgorzata Gacka
Rajmund Adamiec

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