open access
Incidence of Hypertension and Effectivness of Antihypertensive Treatment in Adult Patients after Successful Repair of Coarctation of the Aorta
open access
Abstract
Material and methods We analyzed 93 patients age 17–59 years (the mean age was 29.87 ± 9.72) after a successful operation of the coarctation of the aorta. During control visit blood pressure was measured at rest with the use of mercury sphygmomanometer and current antihypertensive treatment was evaluated. These data were analyzed retrospectively comparing to the blood pressure during the first visit or the visit during which arterial hypertension was diagnosed. Antihypertensive treatment was also analyzed. The patients were observed in the period of 2 months to 5 years.
Results Arterial hypertension was observed in 50 patients (54%) of whom 32 were in stage I, 15 in stage II, and the remaining 3 in stage III according to WHO classification. Antihypertensive management was started with the use of β-blockers or ACE inhibitors in most of the patients. Monotherapy was maintained in 31 patients and 19 required combination therapy. A mean reduction of arterial blood pressure was 12/8 mm Hg. In patients treated with monotherapy blood pressure reduction (8/4 mm Hg) was significantly smaller (p < 0.0001) than in those treated with combination therapy (19/15 mm Hg). Normalization of blood pressure was achieved in 52% patients. The efficacy of monotherapy treatment was 32%, whereas in the group of combination therapy it reached 84%.
Conclusions 1. The prevalence of hypertension in adults after surgical repair of coarctation of the aorta is high and approximates to 50%. 2. Normalization of blood pressure in this group of patients treated by specialists can be achieved in half of the group. 3. Arterial hypertension in adults after surgical repair of coarctation of the aorta is not resistant to treatment, however, the effective control of blood pressure requires a frequent use of combination therapy.
Abstract
Material and methods We analyzed 93 patients age 17–59 years (the mean age was 29.87 ± 9.72) after a successful operation of the coarctation of the aorta. During control visit blood pressure was measured at rest with the use of mercury sphygmomanometer and current antihypertensive treatment was evaluated. These data were analyzed retrospectively comparing to the blood pressure during the first visit or the visit during which arterial hypertension was diagnosed. Antihypertensive treatment was also analyzed. The patients were observed in the period of 2 months to 5 years.
Results Arterial hypertension was observed in 50 patients (54%) of whom 32 were in stage I, 15 in stage II, and the remaining 3 in stage III according to WHO classification. Antihypertensive management was started with the use of β-blockers or ACE inhibitors in most of the patients. Monotherapy was maintained in 31 patients and 19 required combination therapy. A mean reduction of arterial blood pressure was 12/8 mm Hg. In patients treated with monotherapy blood pressure reduction (8/4 mm Hg) was significantly smaller (p < 0.0001) than in those treated with combination therapy (19/15 mm Hg). Normalization of blood pressure was achieved in 52% patients. The efficacy of monotherapy treatment was 32%, whereas in the group of combination therapy it reached 84%.
Conclusions 1. The prevalence of hypertension in adults after surgical repair of coarctation of the aorta is high and approximates to 50%. 2. Normalization of blood pressure in this group of patients treated by specialists can be achieved in half of the group. 3. Arterial hypertension in adults after surgical repair of coarctation of the aorta is not resistant to treatment, however, the effective control of blood pressure requires a frequent use of combination therapy.
Keywords
coarctation of the aorta; arterial hypertension; antihypertensive therapy


Title
Incidence of Hypertension and Effectivness of Antihypertensive Treatment in Adult Patients after Successful Repair of Coarctation of the Aorta
Journal
Issue
Article type
Original paper
Pages
245-252
Published online
2003-09-24
Page views
492
Article views/downloads
1504
Bibliographic record
Nadciśnienie tętnicze 2003;7(4):245-252.
Keywords
coarctation of the aorta
arterial hypertension
antihypertensive therapy
Authors
Olga Trojnarska
Andrzej Tykarski
Małgorzata Pyda
Andrzej Cieśliński