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Macro- and microelements content in hair of subjects with arterial hypertension
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Abstract
Material and methods The study involved 284 subjects, aged 33–70 years, who were allotted into 2 groups: I — 142 patients with arterial hypertension, II — 142 clinically healthy subjects (controls). Age and sex ratio were similar in the examined groups. Those subjected to the study were not administered any drugs at least 3 months prior to the determination of macro- and microelements. Determinations of trace elements Ca, P, Na, K, Mg, Fe, Zn, Cu, Sr, Ni, Mo, Al, Cd, Pb, Mn, Se, Cr, Co, Li, V, B, Ba, Hg were performed with atomic emission spectrometer with plasmic excitation (ICP MS Philips PU 7000).
Results In group I in comparison to group II (control) higher values of Mn, Al, Cd, Pb, Hg were observed, as well as higher Pb/Se, Cd/Se, Al/Se ratio; but lower values of P, Zn and lower Ca/Pb, Ca/Cd, Ca/Al, Zn/Pb, Zn/Cd, Zn/Al, Fe/Mn, Zn/Mn ratio.
Conclusions 1. Toxic metals: Pb, Cd, Al, Hg may be one of the pathogenic factors of arterial hypertension. 2. Deficit of antioxidative trace elements may point to the necessity of Zn and Se supplementation in hypertensive patients.
Abstract
Material and methods The study involved 284 subjects, aged 33–70 years, who were allotted into 2 groups: I — 142 patients with arterial hypertension, II — 142 clinically healthy subjects (controls). Age and sex ratio were similar in the examined groups. Those subjected to the study were not administered any drugs at least 3 months prior to the determination of macro- and microelements. Determinations of trace elements Ca, P, Na, K, Mg, Fe, Zn, Cu, Sr, Ni, Mo, Al, Cd, Pb, Mn, Se, Cr, Co, Li, V, B, Ba, Hg were performed with atomic emission spectrometer with plasmic excitation (ICP MS Philips PU 7000).
Results In group I in comparison to group II (control) higher values of Mn, Al, Cd, Pb, Hg were observed, as well as higher Pb/Se, Cd/Se, Al/Se ratio; but lower values of P, Zn and lower Ca/Pb, Ca/Cd, Ca/Al, Zn/Pb, Zn/Cd, Zn/Al, Fe/Mn, Zn/Mn ratio.
Conclusions 1. Toxic metals: Pb, Cd, Al, Hg may be one of the pathogenic factors of arterial hypertension. 2. Deficit of antioxidative trace elements may point to the necessity of Zn and Se supplementation in hypertensive patients.
Keywords
trace elements; hair; arterial hypertension
Title
Macro- and microelements content in hair of subjects with arterial hypertension
Journal
Issue
Article type
Original paper
Pages
177-184
Published online
2004-06-04
Page views
870
Article views/downloads
2999
Bibliographic record
Nadciśnienie tętnicze 2004;8(3):177-184.
Keywords
trace elements
hair
arterial hypertension
Authors
Aleksander Goch
Jan Henryk Goch