open access

Vol 8, No 4 (2004)
Editorial
Published online: 2004-07-22
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Diagnosis of primary aldosteronism - debate continues. Part I

Aleksander Prejbisz, Mariola Pęczkowska, Andrzej Januszewicz, Włodzimierz Januszewicz
Nadciśnienie tętnicze 2004;8(4):205-214.

open access

Vol 8, No 4 (2004)
Artykuły redakcyjne
Published online: 2004-07-22

Abstract

Primary aldosteronism has been first described by Polish doctor, Michał Lityński in 1953. Improved screening methods have showed that primary aldosteronism is more common than it has been previously suspected. It has been estimated that primary aldosteronism affects 5–10% of patients with hypertension. Idiopathic bilateral adrenal hyperplasia and aldosterone producing adrenal adenoma are the leading causes of primary aldosteronism. The diagnosis of primary aldosteronism must be confirmed by demonstrating autonomous aldosterone secretion with confirmatory testing. The subtype evaluation is based on biochemical and localizing methods. Because of the deleterious cardiovascular effects of excess of aldosterone, normalization of circulating aldosterone or aldosterone receptor blockade should be part of the management plan for all patients with primary aldosteronism.

Abstract

Primary aldosteronism has been first described by Polish doctor, Michał Lityński in 1953. Improved screening methods have showed that primary aldosteronism is more common than it has been previously suspected. It has been estimated that primary aldosteronism affects 5–10% of patients with hypertension. Idiopathic bilateral adrenal hyperplasia and aldosterone producing adrenal adenoma are the leading causes of primary aldosteronism. The diagnosis of primary aldosteronism must be confirmed by demonstrating autonomous aldosterone secretion with confirmatory testing. The subtype evaluation is based on biochemical and localizing methods. Because of the deleterious cardiovascular effects of excess of aldosterone, normalization of circulating aldosterone or aldosterone receptor blockade should be part of the management plan for all patients with primary aldosteronism.
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Keywords

primary aldosteronism; prevalence; screening; diagnosis; treatment

About this article
Title

Diagnosis of primary aldosteronism - debate continues. Part I

Journal

Arterial Hypertension

Issue

Vol 8, No 4 (2004)

Article type

Editorial

Pages

205-214

Published online

2004-07-22

Page views

696

Article views/downloads

3407

Bibliographic record

Nadciśnienie tętnicze 2004;8(4):205-214.

Keywords

primary aldosteronism
prevalence
screening
diagnosis
treatment

Authors

Aleksander Prejbisz
Mariola Pęczkowska
Andrzej Januszewicz
Włodzimierz Januszewicz

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