open access

Vol 8, No 5 (2004)
REVIEV
Published online: 2004-11-15
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Do genes influence on hypotensive respons in essential hypertension treatment?

Karolina Jankowska, Jerzy Głuszek
Nadciśnienie tętnicze 2004;8(5):355-363.

open access

Vol 8, No 5 (2004)
REVIEV
Published online: 2004-11-15

Abstract

The genetic aspect of essential hypertension appears more and more frequently in scientific works. Many candidate genes and their polymorphisms are investigated to find if they cause hypertension. Especially the renin-angiotensin-aldosteron system genes, α-adducin gene, β1-adrenergic receptor gene, Gs protein α-subunit gene or G protein β3-subunit gene are considered. The influence of genetic polymorphism on response to changes in lifestyle and anti-hypertensive treatment is also very interesting. This is the way to understand the difference in response to therapy between different patients. Particularly the effects of treatment are often disappointing.
The aim of this paper is to compile data regarding genetic and pharmacogenetic of essential hypertension.

Abstract

The genetic aspect of essential hypertension appears more and more frequently in scientific works. Many candidate genes and their polymorphisms are investigated to find if they cause hypertension. Especially the renin-angiotensin-aldosteron system genes, α-adducin gene, β1-adrenergic receptor gene, Gs protein α-subunit gene or G protein β3-subunit gene are considered. The influence of genetic polymorphism on response to changes in lifestyle and anti-hypertensive treatment is also very interesting. This is the way to understand the difference in response to therapy between different patients. Particularly the effects of treatment are often disappointing.
The aim of this paper is to compile data regarding genetic and pharmacogenetic of essential hypertension.
Get Citation

Keywords

arterial hypertension; gene polymorphism; antihypertensive treatment

About this article
Title

Do genes influence on hypotensive respons in essential hypertension treatment?

Journal

Arterial Hypertension

Issue

Vol 8, No 5 (2004)

Pages

355-363

Published online

2004-11-15

Bibliographic record

Nadciśnienie tętnicze 2004;8(5):355-363.

Keywords

arterial hypertension
gene polymorphism
antihypertensive treatment

Authors

Karolina Jankowska
Jerzy Głuszek

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