open access

Vol 9, No 2 (2005)
Artykuły redakcyjne
Published online: 2005-04-11
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The importance of brain natriuretic peptide in essential hypertension

Aneta Pośnik-Urbańska, Kalina Kawecka-Jaszcz
Nadciśnienie tętnicze 2005;9(2):81-87.

open access

Vol 9, No 2 (2005)
Artykuły redakcyjne
Published online: 2005-04-11

Abstract

The neurohormonal system of natriuretic peptides is involved in cardiovascular regulation. Discovered in 1988 by Sudoh brain natriuretic peptide (BNP) is a 32-aminoacid cardiac hormone, separated from N-terminal part of propeptide, named NT-proBNP. The level of BNP in healthy subjects is low. Its level is increased in heart failure, arterial and pulmonary hypertension, renal insufficiency and in elderly. In women the level of BNP is higher than in men of the same age. Past observations show that the levels of BNP and NT-proBNP in patients with hypertension and left ventricular hypertrophy, lower ejection fraction and diastolic dysfunction is higher. The significance of the natriuretic peptides in patients with hypertension and preserved left ventricular function is largely unknown.

Abstract

The neurohormonal system of natriuretic peptides is involved in cardiovascular regulation. Discovered in 1988 by Sudoh brain natriuretic peptide (BNP) is a 32-aminoacid cardiac hormone, separated from N-terminal part of propeptide, named NT-proBNP. The level of BNP in healthy subjects is low. Its level is increased in heart failure, arterial and pulmonary hypertension, renal insufficiency and in elderly. In women the level of BNP is higher than in men of the same age. Past observations show that the levels of BNP and NT-proBNP in patients with hypertension and left ventricular hypertrophy, lower ejection fraction and diastolic dysfunction is higher. The significance of the natriuretic peptides in patients with hypertension and preserved left ventricular function is largely unknown.
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Keywords

essential hypertension; BNP; left ventricular hypertrophy

About this article
Title

The importance of brain natriuretic peptide in essential hypertension

Journal

Arterial Hypertension

Issue

Vol 9, No 2 (2005)

Pages

81-87

Published online

2005-04-11

Bibliographic record

Nadciśnienie tętnicze 2005;9(2):81-87.

Keywords

essential hypertension
BNP
left ventricular hypertrophy

Authors

Aneta Pośnik-Urbańska
Kalina Kawecka-Jaszcz

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