Vol 9, No 2 (2005)
Editorial
Published online: 2005-04-11
The importance of brain natriuretic peptide in essential hypertension
Aneta Pośnik-Urbańska, Kalina Kawecka-Jaszcz
Nadciśnienie tętnicze 2005;9(2):81-87.
Vol 9, No 2 (2005)
Artykuły redakcyjne
Published online: 2005-04-11
Abstract
The neurohormonal system of natriuretic peptides is involved
in cardiovascular regulation. Discovered in 1988 by Sudoh brain natriuretic peptide (BNP) is a 32-aminoacid cardiac hormone, separated from N-terminal part of propeptide, named NT-proBNP. The level of BNP in
healthy subjects is low. Its level is increased in heart failure, arterial and pulmonary hypertension, renal insufficiency and in elderly. In women the level of BNP is higher than in men
of the same age. Past observations show that the levels of BNP and NT-proBNP in patients with hypertension and left ventricular hypertrophy, lower ejection fraction and diastolic dysfunction is higher. The significance of the natriuretic peptides in patients with hypertension and preserved left ventricular function is largely unknown.
Abstract
The neurohormonal system of natriuretic peptides is involved
in cardiovascular regulation. Discovered in 1988 by Sudoh brain natriuretic peptide (BNP) is a 32-aminoacid cardiac hormone, separated from N-terminal part of propeptide, named NT-proBNP. The level of BNP in
healthy subjects is low. Its level is increased in heart failure, arterial and pulmonary hypertension, renal insufficiency and in elderly. In women the level of BNP is higher than in men
of the same age. Past observations show that the levels of BNP and NT-proBNP in patients with hypertension and left ventricular hypertrophy, lower ejection fraction and diastolic dysfunction is higher. The significance of the natriuretic peptides in patients with hypertension and preserved left ventricular function is largely unknown.
Keywords
essential hypertension; BNP; left ventricular hypertrophy
Title
The importance of brain natriuretic peptide in essential hypertension
Journal
Arterial Hypertension
Issue
Vol 9, No 2 (2005)
Article type
Editorial
Pages
81-87
Published online
2005-04-11
Page views
577
Article views/downloads
1055
Bibliographic record
Nadciśnienie tętnicze 2005;9(2):81-87.
Keywords
essential hypertension
BNP
left ventricular hypertrophy
Authors
Aneta Pośnik-Urbańska
Kalina Kawecka-Jaszcz