A case report of a patient with Sneddon’s syndrome in 16-year follow-up

Abstract

Sneddon syndrome is an autoimmune disease of unknown ethiology with combination of livedo reticularis, cerebrovascular episodes and arterial hypertension. The anticardiolipin antibodies, antiphospholipid antibodies and lupus anticoagulant play a main role in the pathogenesis. The diagnostic investigations including: anticardiolipin antibodies, skin biopsy, abdominal CT angiography and brain MRI are necessary to recognize the disease.
The case of Sneddon’s syndrome in a 49 year-old woman who developed arterial hypertension, cerebral ischaemic signs, renal injury and who had livedo reticularis is reported.
The diagnostic difficulties, many vascular, cerebral and renal complications and difficulties with treatment during 16-years observation are presented. After immunosupresive, antiplatet and anticoagulant therapy implementation a few years remission was achieved.