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Vol 10, No 2 (2006)
Review paper
Published online: 2006-04-18
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Endothelial function in patients with cardiovascular diseases. Part II: endothelial dysfunction in patients with hypertension and coronary heart disease

Rafał Poręba, Arkadiusz Derkacz, Małgorzata Poręba, Ryszard Andrzejak
Nadciśnienie tętnicze 2006;10(2):147-152.

open access

Vol 10, No 2 (2006)
REVIEV
Published online: 2006-04-18

Abstract

At present it is thought that there may be the connection between subclinical inflammatory conditions and the incidence of hypertension. Up till now it has not been yet established clearly if the increased levels of inflammatory process markers result from primary inflammation promoting the development of atherosclerosis and hypertension or if this phenomenon is only secondary to the impairment of vascular wall in the course of hypertensive disease. It seems that endothelial dysfunction accompanying some inflammatory conditions may be an important clue in pathogeny of primary hypertension. Endothelial dysfunction takes an important part as well in the development as in the clinical evaluation of circulatory system diseases including hypertension and coronary heart disease and is related to increased risk of cardiac events. In some cases of genetically associated hypertension the endothelial dysfunction is primary to the development of hypertension which indicates that it may be the cause of hypertension. On the other hand hypertension itself regardless of its primary cause may impair the function of endothelium.

Abstract

At present it is thought that there may be the connection between subclinical inflammatory conditions and the incidence of hypertension. Up till now it has not been yet established clearly if the increased levels of inflammatory process markers result from primary inflammation promoting the development of atherosclerosis and hypertension or if this phenomenon is only secondary to the impairment of vascular wall in the course of hypertensive disease. It seems that endothelial dysfunction accompanying some inflammatory conditions may be an important clue in pathogeny of primary hypertension. Endothelial dysfunction takes an important part as well in the development as in the clinical evaluation of circulatory system diseases including hypertension and coronary heart disease and is related to increased risk of cardiac events. In some cases of genetically associated hypertension the endothelial dysfunction is primary to the development of hypertension which indicates that it may be the cause of hypertension. On the other hand hypertension itself regardless of its primary cause may impair the function of endothelium.

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Keywords

endothelium; hypertension; coronary heart disease

About this article
Title

Endothelial function in patients with cardiovascular diseases. Part II: endothelial dysfunction in patients with hypertension and coronary heart disease

Journal

Arterial Hypertension

Issue

Vol 10, No 2 (2006)

Article type

Review paper

Pages

147-152

Published online

2006-04-18

Page views

776

Article views/downloads

1374

Bibliographic record

Nadciśnienie tętnicze 2006;10(2):147-152.

Keywords

endothelium
hypertension
coronary heart disease

Authors

Rafał Poręba
Arkadiusz Derkacz
Małgorzata Poręba
Ryszard Andrzejak

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