open access

Vol 11, No 4 (2007)
Prace oryginalne
Published online: 2007-09-07
Get Citation

The impact of carotid intima - media complex index selection for the investigation of a correlation with chosen cardiovascular risk factors

Katarzyna Kunicka, Leszek Bieniaszewski, Ewa Świerblewska, Hanna Świątek, Przybysława Kaczmarek-Kusznierewicz, Piotr Kruszewski, Jolanta Neubauer-Geryk, Eliza Miszkowska, Edyta Drzazga
Nadciśnienie tętnicze 2007;11(4):335-349.

open access

Vol 11, No 4 (2007)
Prace oryginalne
Published online: 2007-09-07

Abstract

Background Carotid intima-media thickness (IMT) is widely used in clinical research. There is strong evidence that increased IMT is a powerful predictor of cardiovascular complications. Varies indices of IMT are used in different studies. So far there is no agreement which marker best reflects cardiovascular risk. Therefore the aim of the study was to establish the association between chosen cardiovascular risk factors and different indices of IMT.
Material and methods 90 males (mean age: 46 ± 8 yrs, BMI 27.7 ± 3.6 kg/m2, office blood pressure 129 ± 8/81 ± 7 mm Hg, 24-hour ambulatory blood pressure: SBP - 125.9 ± 7.9; DBP: 79.7 ± 6.3, total cholesterol 237 ± 35.7 mg/dl, HDL 52 ± 13, TG 184 ± 99) were studied. Doppler echocardiography with systolic and diastolic function evaluation was performed using ALOKA 5000 machine. CIMT measurement was obtained by analysis of ultrasonographic images with dedicated software. Varies indices of common carotid intima–media complex including average IMT, maximal IMT, average cross-sectional area of IMT (CSA-IMT), relative average IMT, relativemaximal IMT and relative CSA-IMT were calculated. The relationship between traditional risk factors and indices of IMT was analyzed by means of multiple regression.
Results The analysis revealed the highest MR coefficients for relative average IMT (R = 0.689) and relative CSAIMT (R = 0.685). Relative average IMT was significantly determined by age (p < 0.001), HDL-cholesterol level (p = 0.02) and 24-ABPM night heart rate (p = 0.035). Relative CSA-IMT was significantly determined by age (p < 0.001), HDL-cholesterol level (p = 0.02), 24-ABPM night heart rate (p = 0.025), BMI (p = 0.045) and fasting glucose level (p = 0.021).
Conclusions Among varies common carotid IM indices relative CSA-IMT may be the best marker of cardiovascular risk. Assessment of this variable may lead to a more precise stratification of the global cardiovascular risk. Arterial Hypertension 2007, vol. 11, no 4, pages 335-349.

Abstract

Background Carotid intima-media thickness (IMT) is widely used in clinical research. There is strong evidence that increased IMT is a powerful predictor of cardiovascular complications. Varies indices of IMT are used in different studies. So far there is no agreement which marker best reflects cardiovascular risk. Therefore the aim of the study was to establish the association between chosen cardiovascular risk factors and different indices of IMT.
Material and methods 90 males (mean age: 46 ± 8 yrs, BMI 27.7 ± 3.6 kg/m2, office blood pressure 129 ± 8/81 ± 7 mm Hg, 24-hour ambulatory blood pressure: SBP - 125.9 ± 7.9; DBP: 79.7 ± 6.3, total cholesterol 237 ± 35.7 mg/dl, HDL 52 ± 13, TG 184 ± 99) were studied. Doppler echocardiography with systolic and diastolic function evaluation was performed using ALOKA 5000 machine. CIMT measurement was obtained by analysis of ultrasonographic images with dedicated software. Varies indices of common carotid intima–media complex including average IMT, maximal IMT, average cross-sectional area of IMT (CSA-IMT), relative average IMT, relativemaximal IMT and relative CSA-IMT were calculated. The relationship between traditional risk factors and indices of IMT was analyzed by means of multiple regression.
Results The analysis revealed the highest MR coefficients for relative average IMT (R = 0.689) and relative CSAIMT (R = 0.685). Relative average IMT was significantly determined by age (p < 0.001), HDL-cholesterol level (p = 0.02) and 24-ABPM night heart rate (p = 0.035). Relative CSA-IMT was significantly determined by age (p < 0.001), HDL-cholesterol level (p = 0.02), 24-ABPM night heart rate (p = 0.025), BMI (p = 0.045) and fasting glucose level (p = 0.021).
Conclusions Among varies common carotid IM indices relative CSA-IMT may be the best marker of cardiovascular risk. Assessment of this variable may lead to a more precise stratification of the global cardiovascular risk. Arterial Hypertension 2007, vol. 11, no 4, pages 335-349.
Get Citation

Keywords

IMT; risk factors

About this article
Title

The impact of carotid intima - media complex index selection for the investigation of a correlation with chosen cardiovascular risk factors

Journal

Arterial Hypertension

Issue

Vol 11, No 4 (2007)

Pages

335-349

Published online

2007-09-07

Bibliographic record

Nadciśnienie tętnicze 2007;11(4):335-349.

Keywords

IMT
risk factors

Authors

Katarzyna Kunicka
Leszek Bieniaszewski
Ewa Świerblewska
Hanna Świątek
Przybysława Kaczmarek-Kusznierewicz
Piotr Kruszewski
Jolanta Neubauer-Geryk
Eliza Miszkowska
Edyta Drzazga

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk

tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail: viamedica@viamedica.pl