open access

Vol 12, No 2 (2008)
Prace oryginalne
Published online: 2008-04-03
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Left ventricular mass and pulse wave velocity in patients with masked hypertension and white-coat hypertension

Katarzyna Stolarz-Skrzypek, Agnieszka Olszanecka, Wojciech Lubaszewski, Grzegorz Bilo, Barbara Wizner, Agata Adamkiewicz-Piejko, Jolanta Życzkowska, Tomasz Grodzicki, Kalina Kawecka-Jaszcz
Nadciśnienie tętnicze 2008;12(2):80-86.

open access

Vol 12, No 2 (2008)
Prace oryginalne
Published online: 2008-04-03

Abstract

Background The aim of the study was to assess the arterial stiffness in subjects with masked hypertension and in subjects with white coat hypertension as compared to hypertensives and normotensives.
Material and methods The study group included 259 untreated subjects (age = 32.8 ± 12.9 years, 136 F/123 M). The 24-h ABP monitoring was performed using oscillometric SpaceLabs 90207 monitors. Two-dimensionally guided M-mode echocardiography was performed (Sonos 5000). Left vetricular mass (LVM) was calculated according to Devereaux formula, and indexed to body surface area (LVMI). Pulse wave velocity (PWV) between the common carotid and femoral artery was measured with the Complior® device.
Results. Among investigated group, masked hypertension was diagnosed in 37 subjects (14.3%), and white coat hypertension in 20 subjects (7.7%). Subjects with masked hypertension as compared to normotensives had higher LVMI (104.7 ± 29.0 - 91.0 ± 16.3 g/m2, p < 0.05) and PWV (10.15 ± 1.62 - 8.56 ± 1.45 m/s, p < 0.05). Also subjects with white coat hypertension as compared to normotensives had higher LVMI (97.6 ± 18.3 vs. 91.0 ± 16.3 g/m2, p < 0.05) and PWV (9.39 ± 1.23 vs. 8.56 ± ± 1.45 m/s, p < 0.05). In the multifactorial analysis, with adjustment applied for age, gender, BMI, smoking and alcohol intake, we observed significant relation of masked hypertension with higher LVMI (p < 0.01) and PWV (p < 0.05). Such relation was not present for white coat hypertension.
Conclusion Masked hypertension is independent determinant of left ventricular hypertrophy and increased arterial stiffness.

Abstract

Background The aim of the study was to assess the arterial stiffness in subjects with masked hypertension and in subjects with white coat hypertension as compared to hypertensives and normotensives.
Material and methods The study group included 259 untreated subjects (age = 32.8 ± 12.9 years, 136 F/123 M). The 24-h ABP monitoring was performed using oscillometric SpaceLabs 90207 monitors. Two-dimensionally guided M-mode echocardiography was performed (Sonos 5000). Left vetricular mass (LVM) was calculated according to Devereaux formula, and indexed to body surface area (LVMI). Pulse wave velocity (PWV) between the common carotid and femoral artery was measured with the Complior® device.
Results. Among investigated group, masked hypertension was diagnosed in 37 subjects (14.3%), and white coat hypertension in 20 subjects (7.7%). Subjects with masked hypertension as compared to normotensives had higher LVMI (104.7 ± 29.0 - 91.0 ± 16.3 g/m2, p < 0.05) and PWV (10.15 ± 1.62 - 8.56 ± 1.45 m/s, p < 0.05). Also subjects with white coat hypertension as compared to normotensives had higher LVMI (97.6 ± 18.3 vs. 91.0 ± 16.3 g/m2, p < 0.05) and PWV (9.39 ± 1.23 vs. 8.56 ± ± 1.45 m/s, p < 0.05). In the multifactorial analysis, with adjustment applied for age, gender, BMI, smoking and alcohol intake, we observed significant relation of masked hypertension with higher LVMI (p < 0.01) and PWV (p < 0.05). Such relation was not present for white coat hypertension.
Conclusion Masked hypertension is independent determinant of left ventricular hypertrophy and increased arterial stiffness.
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Keywords

masked hypertension; white coat hypertension; left ventricular mass; pulse wave velocity

About this article
Title

Left ventricular mass and pulse wave velocity in patients with masked hypertension and white-coat hypertension

Journal

Arterial Hypertension

Issue

Vol 12, No 2 (2008)

Pages

80-86

Published online

2008-04-03

Bibliographic record

Nadciśnienie tętnicze 2008;12(2):80-86.

Keywords

masked hypertension
white coat hypertension
left ventricular mass
pulse wave velocity

Authors

Katarzyna Stolarz-Skrzypek
Agnieszka Olszanecka
Wojciech Lubaszewski
Grzegorz Bilo
Barbara Wizner
Agata Adamkiewicz-Piejko
Jolanta Życzkowska
Tomasz Grodzicki
Kalina Kawecka-Jaszcz

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