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Left ventricular mass and pulse wave velocity in patients with masked hypertension and white-coat hypertension
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Abstract
Material and methods The study group included 259 untreated subjects (age = 32.8 ± 12.9 years, 136 F/123 M). The 24-h ABP monitoring was performed using oscillometric SpaceLabs 90207 monitors. Two-dimensionally guided M-mode echocardiography was performed (Sonos 5000). Left vetricular mass (LVM) was calculated according to Devereaux formula, and indexed to body surface area (LVMI). Pulse wave velocity (PWV) between the common carotid and femoral artery was measured with the Complior® device.
Results. Among investigated group, masked hypertension was diagnosed in 37 subjects (14.3%), and white coat hypertension in 20 subjects (7.7%). Subjects with masked hypertension as compared to normotensives had higher LVMI (104.7 ± 29.0 - 91.0 ± 16.3 g/m2, p < 0.05) and PWV (10.15 ± 1.62 - 8.56 ± 1.45 m/s, p < 0.05). Also subjects with white coat hypertension as compared to normotensives had higher LVMI (97.6 ± 18.3 vs. 91.0 ± 16.3 g/m2, p < 0.05) and PWV (9.39 ± 1.23 vs. 8.56 ± ± 1.45 m/s, p < 0.05). In the multifactorial analysis, with adjustment applied for age, gender, BMI, smoking and alcohol intake, we observed significant relation of masked hypertension with higher LVMI (p < 0.01) and PWV (p < 0.05). Such relation was not present for white coat hypertension.
Conclusion Masked hypertension is independent determinant of left ventricular hypertrophy and increased arterial stiffness.
Abstract
Material and methods The study group included 259 untreated subjects (age = 32.8 ± 12.9 years, 136 F/123 M). The 24-h ABP monitoring was performed using oscillometric SpaceLabs 90207 monitors. Two-dimensionally guided M-mode echocardiography was performed (Sonos 5000). Left vetricular mass (LVM) was calculated according to Devereaux formula, and indexed to body surface area (LVMI). Pulse wave velocity (PWV) between the common carotid and femoral artery was measured with the Complior® device.
Results. Among investigated group, masked hypertension was diagnosed in 37 subjects (14.3%), and white coat hypertension in 20 subjects (7.7%). Subjects with masked hypertension as compared to normotensives had higher LVMI (104.7 ± 29.0 - 91.0 ± 16.3 g/m2, p < 0.05) and PWV (10.15 ± 1.62 - 8.56 ± 1.45 m/s, p < 0.05). Also subjects with white coat hypertension as compared to normotensives had higher LVMI (97.6 ± 18.3 vs. 91.0 ± 16.3 g/m2, p < 0.05) and PWV (9.39 ± 1.23 vs. 8.56 ± ± 1.45 m/s, p < 0.05). In the multifactorial analysis, with adjustment applied for age, gender, BMI, smoking and alcohol intake, we observed significant relation of masked hypertension with higher LVMI (p < 0.01) and PWV (p < 0.05). Such relation was not present for white coat hypertension.
Conclusion Masked hypertension is independent determinant of left ventricular hypertrophy and increased arterial stiffness.
Keywords
masked hypertension; white coat hypertension; left ventricular mass; pulse wave velocity
Title
Left ventricular mass and pulse wave velocity in patients with masked hypertension and white-coat hypertension
Journal
Issue
Article type
Original paper
Pages
80-86
Published online
2008-04-03
Page views
533
Article views/downloads
1171
Bibliographic record
Nadciśnienie tętnicze 2008;12(2):80-86.
Keywords
masked hypertension
white coat hypertension
left ventricular mass
pulse wave velocity
Authors
Katarzyna Stolarz-Skrzypek
Agnieszka Olszanecka
Wojciech Lubaszewski
Grzegorz Bilo
Barbara Wizner
Agata Adamkiewicz-Piejko
Jolanta Życzkowska
Tomasz Grodzicki
Kalina Kawecka-Jaszcz