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Relationship between hyperuricemia and other of cardiovascular risk factors in patients with essential, untreated arterial hypertension in the population of RISK study
open access
Abstract
Material and methods 266 patients with primary, untreated arterial hypertension aged 39 to 75 (mean age 53.2 ± 8.9) were studied. The prevalence of different cardiovascular risk factor eg. cigarette smoking, obesity, high total cholesterol, triglycerides, creatinine and glucose level was compared in subgroups of different uric acid concentration using chi square test.
Results Hyperuricemia was found in 41 of 266 patients. The strongest relationship was observed between uric acid level and creatinine level. The mean creatinine level in HU group was 93.5 μmol/l vs. 84.8 μmol/l in NU group (p = 0.0029). The prevalence of typical cardiovascular risk factors was not significantly different between HU and NU group.
Conclusion The prevalence of hyperuricemia in Polish population of untreated hypertensive patients is around 15%. Results confirmed that uric acid is a marker of renal dysfunction progression, but hyperuricemia was not associated with statistical higher prevalence of established cardiovascular risk factors in hypertensive patients.
Abstract
Material and methods 266 patients with primary, untreated arterial hypertension aged 39 to 75 (mean age 53.2 ± 8.9) were studied. The prevalence of different cardiovascular risk factor eg. cigarette smoking, obesity, high total cholesterol, triglycerides, creatinine and glucose level was compared in subgroups of different uric acid concentration using chi square test.
Results Hyperuricemia was found in 41 of 266 patients. The strongest relationship was observed between uric acid level and creatinine level. The mean creatinine level in HU group was 93.5 μmol/l vs. 84.8 μmol/l in NU group (p = 0.0029). The prevalence of typical cardiovascular risk factors was not significantly different between HU and NU group.
Conclusion The prevalence of hyperuricemia in Polish population of untreated hypertensive patients is around 15%. Results confirmed that uric acid is a marker of renal dysfunction progression, but hyperuricemia was not associated with statistical higher prevalence of established cardiovascular risk factors in hypertensive patients.
Keywords
hypertension; hyperuricemia; metabolic syndrome
Title
Relationship between hyperuricemia and other of cardiovascular risk factors in patients with essential, untreated arterial hypertension in the population of RISK study
Journal
Issue
Article type
Original paper
Pages
190-199
Published online
2008-05-29
Page views
787
Article views/downloads
2436
Bibliographic record
Nadciśnienie tętnicze 2008;12(3):190-199.
Keywords
hypertension
hyperuricemia
metabolic syndrome
Authors
Katarzyna Kostka-Jeziorny
Andrzej Tykarski