open access

Vol 12, No 4 (2008)
Prace oryginalne
Published online: 2008-09-01
Get Citation

Cardiovascular risk factors in hypertensive patients with positive or negative family history of premature cardiovascular diseases – the RISK study population

Katarzyna Kolasińska-Malkowska, Arkadiusz Niklas, Paweł Łopatka, Anna Posadzy-Małaczyńska, Andrzej Tykarski
Nadciśnienie tętnicze 2008;12(4):277-284.

open access

Vol 12, No 4 (2008)
Prace oryginalne
Published online: 2008-09-01

Abstract

Background Positive family history of premature cardiovascular events is considered a significant risk factor of cardiovascular morbidity and mortality.
Objective Comparison of cardiovascular risk factors prevalence in patients with mild to moderate uncomplicated hypertension according to positive or negative family history of premature cardiovascular events in the RISK study population.
Material and methods 1040 patients with grade 1 or 2 new-onset or untreated essential hypertension, aged 53.5 (± 10.1) years admitted to specialist outpatient clinics in Poland were included in the study. The prevalence of high10-years cardiovascular death risk (> 5% according to SCORE charts for high-risk regions of Europe), moderate hypertension, isolated systolic hypertension, smoking, high heart rate, obesity, metabolic syndrome and increased total cholesterol, LDL, HDL, TG, uric acid, glucose levels were compared in two subgroups – with positive (n = 298) and negative (n = 742) family history of premature cardiovascular events using chi square test.
Results Hypertension stage 2, increased T-Chol, LDL-Chol, TG, decreased HDL-Chol, obesity, metabolic syndrome, cigarette smoking and high heart rate have been found significantly more frequently in the positive family history group than in the negative family history group. Prevalences of isolated systolic hypertension, abnormally high uric acid and glucose levels and SCORE ≥ 5% were not significantly different.
Conclusion Positive family history of premature cardiovascular events seems to be associated with higher prevalence of several classic cardiovascular risk factors.

Abstract

Background Positive family history of premature cardiovascular events is considered a significant risk factor of cardiovascular morbidity and mortality.
Objective Comparison of cardiovascular risk factors prevalence in patients with mild to moderate uncomplicated hypertension according to positive or negative family history of premature cardiovascular events in the RISK study population.
Material and methods 1040 patients with grade 1 or 2 new-onset or untreated essential hypertension, aged 53.5 (± 10.1) years admitted to specialist outpatient clinics in Poland were included in the study. The prevalence of high10-years cardiovascular death risk (> 5% according to SCORE charts for high-risk regions of Europe), moderate hypertension, isolated systolic hypertension, smoking, high heart rate, obesity, metabolic syndrome and increased total cholesterol, LDL, HDL, TG, uric acid, glucose levels were compared in two subgroups – with positive (n = 298) and negative (n = 742) family history of premature cardiovascular events using chi square test.
Results Hypertension stage 2, increased T-Chol, LDL-Chol, TG, decreased HDL-Chol, obesity, metabolic syndrome, cigarette smoking and high heart rate have been found significantly more frequently in the positive family history group than in the negative family history group. Prevalences of isolated systolic hypertension, abnormally high uric acid and glucose levels and SCORE ≥ 5% were not significantly different.
Conclusion Positive family history of premature cardiovascular events seems to be associated with higher prevalence of several classic cardiovascular risk factors.
Get Citation

Keywords

hypertension; cardiovascular risk factors; family history

About this article
Title

Cardiovascular risk factors in hypertensive patients with positive or negative family history of premature cardiovascular diseases – the RISK study population

Journal

Arterial Hypertension

Issue

Vol 12, No 4 (2008)

Pages

277-284

Published online

2008-09-01

Bibliographic record

Nadciśnienie tętnicze 2008;12(4):277-284.

Keywords

hypertension
cardiovascular risk factors
family history

Authors

Katarzyna Kolasińska-Malkowska
Arkadiusz Niklas
Paweł Łopatka
Anna Posadzy-Małaczyńska
Andrzej Tykarski

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk

tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail: viamedica@viamedica.pl