Ankle-brachial index and other risk factors of diastolic dysfunction of the left ventricle

Abstract

Background Diastolic dysfunction of the left ventricle is a risk factor of cardiovascular complications. The aim of the study was to determine the diastolic dysfunction of the left ventricle with the use of echocardiography in the rural population according to coexisting risk factors.
Material and methods The study was performed in 178 people (mean age 53.9 ± 13.5), inhabitants of a village of Boguszyce. The diastolic function of left ventricle was assessed by echocardiography, by various parameters including E and A waves, E/A ratio, deceleration time (DT) of E (DTE) and isovolumetric relaxation time (IVRT). In the studied population BMI, systolic and diastolic arterial pressures, lipid parameters and ankle/arm index were measured.
Results In a model of logistic regression analysis it was revealed that independent risk factors of diastolic left ventricle dysfunction incidence are: age (OR: 1.11; p < 0.01), high BMI (OR: 1.02; p < 0.05), arterial hypertension (OR: 1.61; p < 0.05), low ankle–brachial index (OR: 0.52; p < 0.05) and low HDL cholesterol level (OR: 0.98; p < 0.05).
Conclusion We conclude that diastolic dysfunction of the left ventricle is more common in patients with multiple risk factors of cardiovascular diseases.