Vol 12, No 6 (2008)
Review paper
Published online: 2008-12-11
IMT and cardiovascular risk
Barbara Pręgowska-Chwała, Jerzy Pręgowski, Andrzej Januszewicz
Nadciśnienie tętnicze 2008;12(6):454-463.
Vol 12, No 6 (2008)
REVIEV
Published online: 2008-12-11
Abstract
Early signs of target organ damage are one of the main topics
of recent research in hypertension. These include endothelial
dysfunction, microalbuminuria, increased renal resistance index
and increased thickness of intima-media complex (IMT).
Results of IMT measurements performed with Doppler ultrasonography
correlates very well with those from necropsy
studies. Moreover, IMT assessment is relatively easy, noninvasive,
does not require very sophisticated equipment
and correlates with cardiovascular risk factors and clinical
outcome. Therefore it is feasible to use IMT as an endpoint
in large scale population based studies as well as a tool in
potential screening projects. The aim of our review is to
discuss the methodology, results of clinical trials and the
role of IMT measurements in current clinical practice.
Abstract
Early signs of target organ damage are one of the main topics
of recent research in hypertension. These include endothelial
dysfunction, microalbuminuria, increased renal resistance index
and increased thickness of intima-media complex (IMT).
Results of IMT measurements performed with Doppler ultrasonography
correlates very well with those from necropsy
studies. Moreover, IMT assessment is relatively easy, noninvasive,
does not require very sophisticated equipment
and correlates with cardiovascular risk factors and clinical
outcome. Therefore it is feasible to use IMT as an endpoint
in large scale population based studies as well as a tool in
potential screening projects. The aim of our review is to
discuss the methodology, results of clinical trials and the
role of IMT measurements in current clinical practice.
Keywords
carotid IMT; early target organ damage; cardiovascular events
Title
IMT and cardiovascular risk
Journal
Arterial Hypertension
Issue
Vol 12, No 6 (2008)
Article type
Review paper
Pages
454-463
Published online
2008-12-11
Page views
750
Article views/downloads
5923
Bibliographic record
Nadciśnienie tętnicze 2008;12(6):454-463.
Keywords
carotid IMT
early target organ damage
cardiovascular events
Authors
Barbara Pręgowska-Chwała
Jerzy Pręgowski
Andrzej Januszewicz