open access

Vol 12, No 6 (2008)
REVIEV
Published online: 2008-12-11
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IMT and cardiovascular risk

Barbara Pręgowska-Chwała, Jerzy Pręgowski, Andrzej Januszewicz
Nadciśnienie tętnicze 2008;12(6):454-463.

open access

Vol 12, No 6 (2008)
REVIEV
Published online: 2008-12-11

Abstract

Early signs of target organ damage are one of the main topics of recent research in hypertension. These include endothelial dysfunction, microalbuminuria, increased renal resistance index and increased thickness of intima-media complex (IMT). Results of IMT measurements performed with Doppler ultrasonography correlates very well with those from necropsy studies. Moreover, IMT assessment is relatively easy, noninvasive, does not require very sophisticated equipment and correlates with cardiovascular risk factors and clinical outcome. Therefore it is feasible to use IMT as an endpoint in large scale population based studies as well as a tool in potential screening projects. The aim of our review is to discuss the methodology, results of clinical trials and the role of IMT measurements in current clinical practice.

Abstract

Early signs of target organ damage are one of the main topics of recent research in hypertension. These include endothelial dysfunction, microalbuminuria, increased renal resistance index and increased thickness of intima-media complex (IMT). Results of IMT measurements performed with Doppler ultrasonography correlates very well with those from necropsy studies. Moreover, IMT assessment is relatively easy, noninvasive, does not require very sophisticated equipment and correlates with cardiovascular risk factors and clinical outcome. Therefore it is feasible to use IMT as an endpoint in large scale population based studies as well as a tool in potential screening projects. The aim of our review is to discuss the methodology, results of clinical trials and the role of IMT measurements in current clinical practice.
Get Citation

Keywords

carotid IMT; early target organ damage; cardiovascular events

About this article
Title

IMT and cardiovascular risk

Journal

Arterial Hypertension

Issue

Vol 12, No 6 (2008)

Pages

454-463

Published online

2008-12-11

Bibliographic record

Nadciśnienie tętnicze 2008;12(6):454-463.

Keywords

carotid IMT
early target organ damage
cardiovascular events

Authors

Barbara Pręgowska-Chwała
Jerzy Pręgowski
Andrzej Januszewicz

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