Relationship between renal resistive index and target organ damage in patiens with treated primary hypertension

Abstract

Background The objective of the study was to evaluate renal resistive index (RI) value in patients with treated hypertension in relation to ABPM values and target organ damage. Material and methods The study included two groups. Group 1 consisted of 125 patients aged 51.2 ± 12.2 with treated essential hypertension (EH), group 2 consisted of 95 normotensive, healthy subjects aged 37.9 ± 10.4. In both groups biochemical evaluations, ABPM, echocardiography, carotid and renal arteries ultrasound and Doppler studies were performed. Results RI values in patients with treated EH were significantly higher as compared to RI values in the normotensive, control group (0.63 ± 0,07 vs. 0.59 ± 0.05; p < 0.01). This difference was still significant after dividing according to the sex. PI values in EH group were also significantly higher as compared with control group. In an univariate analysis, in the hypertensive group, RI values correlated with age, PP and AASI values, mean 24-h diastolic blood pressure values, GFR, carotid IMT and with echocardiographic parameters: E/E’ ratio and RWT. In the multivariate analysis, RI values correlated independently only with carotid IMT. Conclusions In our study renal resistive values were positively correlated with early target organ damage. The resistive index was higher in those with a long-standing treated hypertension as compared to normotensive subjects.