Background Arterial hypertension, treated insufficiently or untreated, is one of main factors leading to the development of atherosclerosis and one of the most frequent causes of cardiovascular morbidity and mortality. The aim of the study was to analyse retrospectively monitoring of arterial hypertension among patients treated in the outpatient clinic and to evaluate effectiveness of the treatment administered.
Material and methods Retrospective analysis of the course and treatment of hypertension was performed based on medical data collected from 164 patients (males n = 79 (47%), females n = 89 (52.9%), mean age 51.6 ± 14.6 years. The study patients were divided into those without concomitant diseases (group I) and patients with concomitant diseases such as, diabetes, atherosclerosis (group II).
Results Basing on the analysis, it was found that the values of arterial pressure were not statistically significantly different in group I (153.6 ± 21.2 mm Hg) and group II (157.6 ± 27.9 mm Hg). Patients from the higher risk group (group II) had elevated BMI (31.6 ± 5.9) in comparison with patients from group I (28.7 ± 5.4) (p < 0.05). A significantly lower ejective fraction (56.2 ± 9.1%) was revealed in patients from group II compared to patients from group I (63.2 ± 4.2%) (p < 0.05). Statistically significant differences were found in the results of biochemical examinations (creatinine concentration, cholesterol concentration, HDL fraction, TG and hemoglobin concentration) in the study groups. The worse kidney function was observed in patients from group II in comparison with patients from group I (creatinine concentration in group I - 0.85 ± 0.21 mg/dl, in group II - 1.16 ± 1.02 mg/dl). Multimedication therapy was administered more frequently to normalize arterial pressure in patients with concomitant diseases compared to patients without concomitant diseases (group I - 0.7%, group II - 6.2%) (p < 0.05).
Conclusions
1. No statistically significant differences were found in the level of arterial pressure in the measurements taken in the study groups.
2. Patients from the higher risk group had the statistically significant worse function of the kidneys.
3. Despite multimedication therapy administered in patients with concomitant diseases, target levels of arterial pressure below 130/80 mmHg were not reached in this group.