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Usefulness of kidney function evaluation in the interpretation of cardiovascular risk in the group of patients with arterial hypertension
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Abstract
Material and methods Assessment of prevalence of CKD using estimating GFR according to Modification of Diet in Renal Disease (MDRD) formula in 58 hospitalized hypertensive patients (20 women and 38 men). They were divided in two groups: A - 28 patients without coronary artery disease (9 women and 19 men) and B - 30 patients with coronary artery disease (11 women and 19 men).
Results According to MDRD formula: stage 1 CKD in the group of hypertensive patients without coronary artery disease (A) was found in 25%, whereas in the group of hypertensive patients with coronary artery disease (B) it was found in 6.67%. Stage 2 CKD in the group of hypertensive patients without coronary artery disease (A) was found in 39.29%, whereas in the group of hypertensive patients with coronary artery disease (B) it was found in 50%. Stage 3 CKD in the group of hypertensive patients without coronary artery disease (A) was found in 14.29%, whereas in the group of hypertensive patients with coronary artery disease (B) it was found in 23.33%.
Conclusions There is a need to estimate GFR according to MDRD formula, because there isn’t a linear dependence between GFR and creatinine concentration. We have to remember that GFR which gives evidence of chronic kidney disease is considered to be a significant cardiovascular risk factor.
Abstract
Material and methods Assessment of prevalence of CKD using estimating GFR according to Modification of Diet in Renal Disease (MDRD) formula in 58 hospitalized hypertensive patients (20 women and 38 men). They were divided in two groups: A - 28 patients without coronary artery disease (9 women and 19 men) and B - 30 patients with coronary artery disease (11 women and 19 men).
Results According to MDRD formula: stage 1 CKD in the group of hypertensive patients without coronary artery disease (A) was found in 25%, whereas in the group of hypertensive patients with coronary artery disease (B) it was found in 6.67%. Stage 2 CKD in the group of hypertensive patients without coronary artery disease (A) was found in 39.29%, whereas in the group of hypertensive patients with coronary artery disease (B) it was found in 50%. Stage 3 CKD in the group of hypertensive patients without coronary artery disease (A) was found in 14.29%, whereas in the group of hypertensive patients with coronary artery disease (B) it was found in 23.33%.
Conclusions There is a need to estimate GFR according to MDRD formula, because there isn’t a linear dependence between GFR and creatinine concentration. We have to remember that GFR which gives evidence of chronic kidney disease is considered to be a significant cardiovascular risk factor.
Keywords
kidney function; cardiovascular risk factor; hypertension; coronary artery disease; GFR
Title
Usefulness of kidney function evaluation in the interpretation of cardiovascular risk in the group of patients with arterial hypertension
Journal
Issue
Article type
Original paper
Pages
410-416
Published online
2010-02-26
Page views
664
Article views/downloads
1334
Bibliographic record
Nadciśnienie tętnicze 2009;13(6):410-416.
Keywords
kidney function
cardiovascular risk factor
hypertension
coronary artery disease
GFR
Authors
Lucyna Woźnicka-Leśkiewicz
Angelika Kuczmarska
Izabela Lipska
Marcin Kordasz
Katarzyna Małaczyńska-Rajpold