open access

Vol 2, No 2 (1997)
Untitled
Published online: 1997-01-01
Submitted:
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Principles of total body irradiation

T. Girinsky, E. Briot, A. Bridier, A. Breaudre
DOI: 10.1016/S1428-2267(97)70118-2
·
Rep Pract Oncol Radiother 1997;2(2):42.

open access

Vol 2, No 2 (1997)
Untitled
Published online: 1997-01-01
Submitted:

Abstract

Total body irradiation delivered prior to bone marrow transplantation remains an important component of the conditioning regimen. Proper engraftment of autologous or allogeneic bone marrow is possible because of the multifarious effects of high doses of ionizing radiation on tumor cells and the host immune system.

We will broadly outline the techniques used to deliver total body irradiation, and the effects of ionizing radiation on normal and tumor cells from a biological and molecular point of view. Finally we will report the results of randomized c1inical trials that have been conducted in our institution during the last ten years.

Abstract

Total body irradiation delivered prior to bone marrow transplantation remains an important component of the conditioning regimen. Proper engraftment of autologous or allogeneic bone marrow is possible because of the multifarious effects of high doses of ionizing radiation on tumor cells and the host immune system.

We will broadly outline the techniques used to deliver total body irradiation, and the effects of ionizing radiation on normal and tumor cells from a biological and molecular point of view. Finally we will report the results of randomized c1inical trials that have been conducted in our institution during the last ten years.

Get Citation
About this article
Title

Principles of total body irradiation

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 2, No 2 (1997)

Pages

42

Published online

1997-01-01

DOI

10.1016/S1428-2267(97)70118-2

Bibliographic record

Rep Pract Oncol Radiother 1997;2(2):42.

Authors

T. Girinsky
E. Briot
A. Bridier
A. Breaudre

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