open access

Vol 4, No 1 (1999)
Case reports
Published online: 1999-01-01
Submitted: 1998-08-31
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Acute pancreatitis during L-asparaginase treatment in children with acute lymphoblastic leukemia

K. Derwich, D. Stencel, M. Warzywoda, M. Leda
DOI: 10.1016/S1507-1367(99)70309-3
·
Rep Pract Oncol Radiother 1999;4(1):15-22.

open access

Vol 4, No 1 (1999)
Case reports
Published online: 1999-01-01
Submitted: 1998-08-31

Abstract

L-asparaginase (L-ASPA) has been put to a wide application in many therapeutic protocols, above all in the treatment of acute lymphoblastic leukemia (ALL). We presented three cases of acute pancreatitis in children with ALL induced by administration of L-ASPA preparations. Our observations revealed that ultrasound investigations are very useful in diagnosis and monitoring changes in the pancreas. The use of L-ASPA derivatives allows to decrease the toxic and allergic sequele resulting from the administration of the drug.

Abstract

L-asparaginase (L-ASPA) has been put to a wide application in many therapeutic protocols, above all in the treatment of acute lymphoblastic leukemia (ALL). We presented three cases of acute pancreatitis in children with ALL induced by administration of L-ASPA preparations. Our observations revealed that ultrasound investigations are very useful in diagnosis and monitoring changes in the pancreas. The use of L-ASPA derivatives allows to decrease the toxic and allergic sequele resulting from the administration of the drug.

Get Citation

Keywords

Acute pancreatitis L-asparaginase; ALL

About this article
Title

Acute pancreatitis during L-asparaginase treatment in children with acute lymphoblastic leukemia

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 4, No 1 (1999)

Pages

15-22

Published online

1999-01-01

DOI

10.1016/S1507-1367(99)70309-3

Bibliographic record

Rep Pract Oncol Radiother 1999;4(1):15-22.

Keywords

Acute pancreatitis L-asparaginase
ALL

Authors

K. Derwich
D. Stencel
M. Warzywoda
M. Leda

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