open access

Vol 3, No 4 (1998)
Review paper
Published online: 1998-01-01
Submitted: 1998-09-07
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Transitory diabetes mellitus in children during treatment of acute lymphoblastic leukemia

D. Stencel, K. Derwich, M. Kaczmarek-Kanold
DOI: 10.1016/S1507-1367(98)70173-7
·
Rep Pract Oncol Radiother 1998;3(4):85-88.

open access

Vol 3, No 4 (1998)
Review paper
Published online: 1998-01-01
Submitted: 1998-09-07

Abstract

Intensification of treatment of acute Iymphoblastic leukemia in children causes the increase of side effects, in this number diabetes mellitus. This disorder has a different character from „real” diabetes, very complicated etiology and most often – transitory duration. The diabetogenic activity is attributed first of all to corticosteroids and L-asparaginase. Early diagnosis and proper treatment (cessation of diabetogenic drugs, a diet and insulin therapy) make possible fast regression of clinical and biochemical abnormalities and, what is the most important, enables a continuation of chemotherapy. We present 3 cases of transitory diabetes mellitus in children with acute lymphoblastic leukemia.

Abstract

Intensification of treatment of acute Iymphoblastic leukemia in children causes the increase of side effects, in this number diabetes mellitus. This disorder has a different character from „real” diabetes, very complicated etiology and most often – transitory duration. The diabetogenic activity is attributed first of all to corticosteroids and L-asparaginase. Early diagnosis and proper treatment (cessation of diabetogenic drugs, a diet and insulin therapy) make possible fast regression of clinical and biochemical abnormalities and, what is the most important, enables a continuation of chemotherapy. We present 3 cases of transitory diabetes mellitus in children with acute lymphoblastic leukemia.

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Keywords

ALL in children; transitory diabetes mellitus

About this article
Title

Transitory diabetes mellitus in children during treatment of acute lymphoblastic leukemia

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 3, No 4 (1998)

Pages

85-88

Published online

1998-01-01

DOI

10.1016/S1507-1367(98)70173-7

Bibliographic record

Rep Pract Oncol Radiother 1998;3(4):85-88.

Keywords

ALL in children
transitory diabetes mellitus

Authors

D. Stencel
K. Derwich
M. Kaczmarek-Kanold

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