Vol 3, No 4 (1998)
Review paper
Published online: 1998-01-01
Large cell anaplastic lypmhoma versus Hodgkin's disease – difficulties in the diagnosis
DOI: 10.1016/S1507-1367(98)70172-5
Rep Pract Oncol Radiother 1998;3(4):81-83.
Abstract
During the last 5 years in the Polish Children's Leukemia/Lymphoma Study Group (7 centers) 241 children with Hodgkin's Disease and 14 children with Large Cell Anaplastic Lymphoma were treated.
In 5 of them we had problems with differential diagnosis.
Immunohistochemical tests:
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CD30 positive, CD15 positive, LCA negative allowed us to change the diagnosis from Large Cell Anaplastic Lymphoma to Hodgkin's Disease (one child) and
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CD30 positive, CD15 negative from Hodgkin's Disease to Large Cell Anaplastic Lymphoma (four children).
All children achieved remission after changing the protocol of chemotherapy.
Keywords: Iymphomas in childrenLCALHD