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Large cell anaplastic lypmhoma versus Hodgkin's disease – difficulties in the diagnosis
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Abstract
During the last 5 years in the Polish Children's Leukemia/Lymphoma Study Group (7 centers) 241 children with Hodgkin's Disease and 14 children with Large Cell Anaplastic Lymphoma were treated.
In 5 of them we had problems with differential diagnosis.
Immunohistochemical tests:
- –
CD30 positive, CD15 positive, LCA negative allowed us to change the diagnosis from Large Cell Anaplastic Lymphoma to Hodgkin's Disease (one child) and
- –
CD30 positive, CD15 negative from Hodgkin's Disease to Large Cell Anaplastic Lymphoma (four children).
All children achieved remission after changing the protocol of chemotherapy.
Abstract
During the last 5 years in the Polish Children's Leukemia/Lymphoma Study Group (7 centers) 241 children with Hodgkin's Disease and 14 children with Large Cell Anaplastic Lymphoma were treated.
In 5 of them we had problems with differential diagnosis.
Immunohistochemical tests:
- –
CD30 positive, CD15 positive, LCA negative allowed us to change the diagnosis from Large Cell Anaplastic Lymphoma to Hodgkin's Disease (one child) and
- –
CD30 positive, CD15 negative from Hodgkin's Disease to Large Cell Anaplastic Lymphoma (four children).
All children achieved remission after changing the protocol of chemotherapy.
Keywords
Iymphomas in children; LCAL; HD
About this articleTitle
Large cell anaplastic lypmhoma versus Hodgkin's disease – difficulties in the diagnosis
Journal
Reports of Practical Oncology and Radiotherapy
Issue
Pages
81-83
Published online
1998-01-01
DOI
10.1016/S1507-1367(98)70172-5
Bibliographic record
Rep Pract Oncol Radiother 1998;3(4):81-83.
Keywords
Iymphomas in children
LCAL
HD
Authors
M. Kaczmarek-Kanold
K. Stefańska
E. Trejster
P. Kołecki
G. Wróbel
B. Sopyło
E. Stańczak