88. Comparison results of different strategies of radiotherapy in nasopharyngeal carcinoma

D. Fundowicz; A. Kruk-Zagajewska; E. Adamiak; M. Matecka-Nowak; P. Milecki; G. Stryczyńska

doi:10.1016/S1507-1367(01)70458-0

Vol 6, No 1 (2001)

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Published online: 2001-01-01

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88. Comparison results of different strategies of radiotherapy in nasopharyngeal carcinoma

D. Fundowicz, A. Kruk-Zagajewska, E. Adamiak, M. Matecka-Nowak, P. Milecki, G. Stryczyńska

DOI: 10.1016/S1507-1367(01)70458-0

Rep Pract Oncol Radiother 2001;6(1):67-68.

Vol 6, No 1 (2001)

Untitled

Published online: 2001-01-01

Submitted:

Abstract

Aim

: Evaluation results of radiotherapy in nasopharyngeal carcinoma in years; 1980–1990 (before CT era) vs 1991–1995.

Material/methods

: One hundred eighty eight patients treated in our centre were included in this analysis. Two groups of patients were distinguished: I-st – 128 patients (treated between 1980–1990) and II-nd – 60 (treated between 1991–1995). The possibilities of diagnosis and radiotherapy techniques were diffrent in both groups. In the II-nd group; the shrinking field technique, CT in diagnosis and target delineation and also higher total dose (mean 66 Gy) were applied.

Results

: For all patients 5-years disease free-survival was 30%. During follow-up the first two years were crucial, because 80% of failures occured. The causes of failures were as follow: the local recurrence (43%), metastases to lymph nodes (39%) and distant metastases (18%).

Conclusions

: Introducing CT into diagnosis and target delineation, the shrinking field technique and higher total dose of irradiation caused in improvement of results of radiotherapy in nasopharyngeal carcinoma.