79. The effectivness of pain treatment with Strontium 89 in patient with osseous metastases

Abstract

Aim

of this study was to assessment of 89 Sr therapy as pain treatment modality in the group of patients with multiple bone metastases.

Material and methods

From January 2000 to October 2000 in our center were treated 41 patients; 17 – prostate cancer and 24 – breast cancer patients. All patients had applied only one dose of 150 MBq of 89 Sr. Before and follow-up each patient has been evaluated; performance status according to the Karnofsky Scale and paro intensity according the VAS scale. We did not observe any clinical important haematological side effects. The ionisation dosemetric monitoring of the sources and the radioactive refuse were recorded. The radioactive refuse was storage in special container when the activity decreased to the background.

Results

We noted relief of paro as follow:

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  “complete” 18 of 41 patients (8-prostate cancer, 10 – breast cancer),

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  “partial” 12 of 41 patients (3- prostate cancer, 9- breast cancer),

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  “no effect” 11 of 41 patients (6-prostate cancer, 5- breast cancer).

Conclusions

We suggest that therapy of painful multiple bone metastases with application of 89 Sr is effective nd safe.