71. The results of postoperative radiotherapy in 63 patients with low-grade gliomas treated in Greatpoland Cancer Center

Abstract

Introduction

Low-grade glicomas represents 15% of all primary brain tumors.

Material and Method

Between 1990–97 63 patient with low-grade gliomas were treated in Greatpoland Cancer Center (39 males, 24 females; age between 20–60 year). 15 patients had andegrone complete surgical excision, 48 partial or subtotal excision of tumor. The frontal lobe was affected in 33 patients, the temporal lobe in 14 patients. Patients received conventional irradiaton of 60 Gy.

Results

^*Five patients with histologically verified pilocytic astrocytomas(I) were treated after partial excision, median of age 29.2 year median survival 58 months (27–108). Only one patient died 27 months after radiotherapy. ^*Thirteen patients with fibrylar astrocytomas(II)-11 post subtotal excision-median age 37.7 year median survival 32.5 months. Recurrent tumor in two patients. Five patients are alive. ^*Ten patients with protoplasmatic astrocytoma(II)-7 post subtotal excision median of age 43.5 year median survival 30.8 months. Four patients alive. ^*Seven patients with gemistocytic astrocytomas(II) (6 post subtotal excision)-median age 36 year, median survival 32 months. Only one patient alive. ^*Eleven patients with oligoastrocytomas(II)-11 post subtotal excision, median age 38.6 year, median survival 43.9 months. Two patients with recrrent tumor. Alive 8 patients. ^*Seventeen patients with oligodendrogliomas (11 post subtotal excision) median age 39 years, median survival 39 months. One patien with recrrent tumor. Alive 8 patients.

Conclusions

^*30 patients are alive(48%); ^*histopathologic diagnosis pilocytic astrocytomas asociated with age 10 years younger then either low-grade gliomas and long-term survivors; ^*poor prognistic factor in gemistocytic astrocytomas-only one patient alive; ^*five patients with recurrent tumor among 17 to 49 months after radiotheraphy.