open access

Vol 25, No 5 (2020)
Original research articles
Published online: 2020-09-01
Submitted: 2019-11-22
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Hypo- vs. normofractionated radiation therapy in breast cancer: A patterns of care analysis in German speaking countries

M. Mayinger, C. Straube, D. Habermehl, M.N. Duma, S.E. Combs
DOI: 10.1016/j.rpor.2020.07.003
·
Rep Pract Oncol Radiother 2020;25(5):775-779.

open access

Vol 25, No 5 (2020)
Original research articles
Published online: 2020-09-01
Submitted: 2019-11-22

Abstract

Aim and background

To assess the use of hypofractionated (HG-RT) versus normofractionated radiation therapy (NF-RT) in Breast Cancer in German speaking countries.

Materials and methods

Between July 2017 and August 2017, an email-based survey was sent to all 1408 physicians that are members of the German Society of Radiation Oncology (DEGRO). The survey was completed by 180 physicians including 10 private practice owners and 52 heads of departments. The majority (82.1%) of the participants had >15 years of experience in radiation therapy (RT).

Results

The majority (83.9%) of the heads of the departments agreed on using the normofractionated regimen of RT as standard treatment for breast cancer. Several physicians were skeptical about HF-RT with 6.5% of the heads refusing to use HF-RT. 40.3% of the departments had not seen the new German guidelines suggesting HF-RT as the standard treatment for all patients as positive or merely adopted a neutral position toward the guidelines (33.9%). The main points of criticism were increased side effects, an impaired toxicity profile and insufficient data. Most departments (46.8%) that perform HF-RT do so in an individual based manner.

Conclusions

HF-RT remains controversial in German speaking countries. Our data shows that NF-RT remains the predominant method of treatment. HF-RT is only used in a defined group of patients as most German physicians agree that particular patients, especially those at higher risk of RT late effects, may benefit from a less intense, extended fractionation schedule.

Abstract

Aim and background

To assess the use of hypofractionated (HG-RT) versus normofractionated radiation therapy (NF-RT) in Breast Cancer in German speaking countries.

Materials and methods

Between July 2017 and August 2017, an email-based survey was sent to all 1408 physicians that are members of the German Society of Radiation Oncology (DEGRO). The survey was completed by 180 physicians including 10 private practice owners and 52 heads of departments. The majority (82.1%) of the participants had >15 years of experience in radiation therapy (RT).

Results

The majority (83.9%) of the heads of the departments agreed on using the normofractionated regimen of RT as standard treatment for breast cancer. Several physicians were skeptical about HF-RT with 6.5% of the heads refusing to use HF-RT. 40.3% of the departments had not seen the new German guidelines suggesting HF-RT as the standard treatment for all patients as positive or merely adopted a neutral position toward the guidelines (33.9%). The main points of criticism were increased side effects, an impaired toxicity profile and insufficient data. Most departments (46.8%) that perform HF-RT do so in an individual based manner.

Conclusions

HF-RT remains controversial in German speaking countries. Our data shows that NF-RT remains the predominant method of treatment. HF-RT is only used in a defined group of patients as most German physicians agree that particular patients, especially those at higher risk of RT late effects, may benefit from a less intense, extended fractionation schedule.

Get Citation

Keywords

DEGRO; Gy; HF-RT; IORT; RT; SIB; SOP; Breast cancer; Patterns of care; Hypofractionated radiotherapy; Normofractionated radiotherapy

About this article
Title

Hypo- vs. normofractionated radiation therapy in breast cancer: A patterns of care analysis in German speaking countries

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 25, No 5 (2020)

Pages

775-779

Published online

2020-09-01

DOI

10.1016/j.rpor.2020.07.003

Bibliographic record

Rep Pract Oncol Radiother 2020;25(5):775-779.

Keywords

DEGRO
Gy
HF-RT
IORT
RT
SIB
SOP
Breast cancer
Patterns of care
Hypofractionated radiotherapy
Normofractionated radiotherapy

Authors

M. Mayinger
C. Straube
D. Habermehl
M.N. Duma
S.E. Combs

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