open access

Vol 25, No 4 (2020)
Reviews
Published online: 2020-07-01
Submitted: 2019-10-27
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Prostatic irradiation-induced sexual dysfunction: A review and multidisciplinary guide to management in the radical radiotherapy era (Part II on Urological Management)

Marc J. Rogers, Marigdalia K. Ramirez-Fort, James A. Kashanian, Seth A. Broster, Jaime Matta, Sean S. Mahase, Digna V. Fort, M. Junaid Niaz, Shearwood McClelland, Neil H. Bander, Migdalia Fort, Christopher S. Lange, Peter Schlegel, John P. Mulhall
DOI: 10.1016/j.rpor.2020.03.011
·
Rep Pract Oncol Radiother 2020;25(4):619-624.

open access

Vol 25, No 4 (2020)
Reviews
Published online: 2020-07-01
Submitted: 2019-10-27

Abstract

Prostate cancer is the most common malignancy in men and the second leading cause of cancer-related death in men. Radiotherapy is a curative option that is administered via external beam radiation, brachytherapy, or in combination. Sexual dysfunction is a common toxicity following radiotherapy, similar to men undergoing radical prostatectomy, but the etiology is different. The pathophysiology of radiation-induced sexual dysfunction is multi-factorial, and the toxicity is a major cause of impaired quality of life among long-term prostate cancer survivors. Management of a patient’s sexual function during and after radiotherapy requires multidisciplinary coordination of care between radiation oncology, urology, psychiatry, pharmacy, and dermatology. This review provides a framework for clinicians to better understand prostatic radiotherapy-induced sexual dysfunction diagnosis, evaluation, and a patient-centered approach to toxicity preventive strategies and management.

Abstract

Prostate cancer is the most common malignancy in men and the second leading cause of cancer-related death in men. Radiotherapy is a curative option that is administered via external beam radiation, brachytherapy, or in combination. Sexual dysfunction is a common toxicity following radiotherapy, similar to men undergoing radical prostatectomy, but the etiology is different. The pathophysiology of radiation-induced sexual dysfunction is multi-factorial, and the toxicity is a major cause of impaired quality of life among long-term prostate cancer survivors. Management of a patient’s sexual function during and after radiotherapy requires multidisciplinary coordination of care between radiation oncology, urology, psychiatry, pharmacy, and dermatology. This review provides a framework for clinicians to better understand prostatic radiotherapy-induced sexual dysfunction diagnosis, evaluation, and a patient-centered approach to toxicity preventive strategies and management.

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Keywords

Prostate cancer; Erectile dysfunction; Ejaculatory dysfunction; Orgasmic dysfunction; Radiation therapy; Sexual Toxicities; PDE-5i; Vacuum erection device; Intracavernosal Injections; Penile Vibratory stimulation; Penile prosthesis

About this article
Title

Prostatic irradiation-induced sexual dysfunction: A review and multidisciplinary guide to management in the radical radiotherapy era (Part II on Urological Management)

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 25, No 4 (2020)

Pages

619-624

Published online

2020-07-01

DOI

10.1016/j.rpor.2020.03.011

Bibliographic record

Rep Pract Oncol Radiother 2020;25(4):619-624.

Keywords

Prostate cancer
Erectile dysfunction
Ejaculatory dysfunction
Orgasmic dysfunction
Radiation therapy
Sexual Toxicities
PDE-5i
Vacuum erection device
Intracavernosal Injections
Penile Vibratory stimulation
Penile prosthesis

Authors

Marc J. Rogers
Marigdalia K. Ramirez-Fort
James A. Kashanian
Seth A. Broster
Jaime Matta
Sean S. Mahase
Digna V. Fort
M. Junaid Niaz
Shearwood McClelland
Neil H. Bander
Migdalia Fort
Christopher S. Lange
Peter Schlegel
John P. Mulhall

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