Vol 25, No 3 (2020)
Review paper
Published online: 2020-05-01

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Cardiotoxicity of radiation therapy in esophageal cancer

Milan Vošmik1, Miroslav Hodek1, David Buka1, Petra Sýkorová1, Jakub Grepl1, Petr Paluska1, Simona Paulíková1, Igor Sirák
DOI: 10.1016/j.rpor.2020.02.005
Rep Pract Oncol Radiother 2020;25(3):318-322.

Abstract

With a development of radiotherapeutic techniques, availability of radiotherapy data on cardiotoxicity, and slowly improving esophageal cancer outcomes, an increasing emphasis is placed on the heart protection in radiation treated esophageal cancer patients. Radiation induced heart complications encompass mainly pericardial disease, cardiomyopathy, coronary artery atherosclerosis, valvular heart disease, and arrhythmias. The most frequent toxicity is pericardial effusion which is usually asymptomatic in the majority of patients. The use of modern radiotherapy techniques is expected to reduce the risk of cardiotoxicity, although this expectation has to be confirmed by clinical data.

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Reports of Practical Oncology and Radiotherapy