open access

Vol 25, No 3 (2020)
Reviews
Published online: 2020-05-01
Submitted: 2019-05-06
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Cardiotoxicity of radiation therapy in esophageal cancer

Milan Vošmik, Miroslav Hodek, David Buka, Petra Sýkorová, Jakub Grepl, Petr Paluska, Simona Paulíková, Igor Sirák
DOI: 10.1016/j.rpor.2020.02.005
·
Rep Pract Oncol Radiother 2020;25(3):318-322.

open access

Vol 25, No 3 (2020)
Reviews
Published online: 2020-05-01
Submitted: 2019-05-06

Abstract

With a development of radiotherapeutic techniques, availability of radiotherapy data on cardiotoxicity, and slowly improving esophageal cancer outcomes, an increasing emphasis is placed on the heart protection in radiation treated esophageal cancer patients. Radiation induced heart complications encompass mainly pericardial disease, cardiomyopathy, coronary artery atherosclerosis, valvular heart disease, and arrhythmias. The most frequent toxicity is pericardial effusion which is usually asymptomatic in the majority of patients. The use of modern radiotherapy techniques is expected to reduce the risk of cardiotoxicity, although this expectation has to be confirmed by clinical data.

Abstract

With a development of radiotherapeutic techniques, availability of radiotherapy data on cardiotoxicity, and slowly improving esophageal cancer outcomes, an increasing emphasis is placed on the heart protection in radiation treated esophageal cancer patients. Radiation induced heart complications encompass mainly pericardial disease, cardiomyopathy, coronary artery atherosclerosis, valvular heart disease, and arrhythmias. The most frequent toxicity is pericardial effusion which is usually asymptomatic in the majority of patients. The use of modern radiotherapy techniques is expected to reduce the risk of cardiotoxicity, although this expectation has to be confirmed by clinical data.

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Keywords

Esophageal cancer; Radiation therapy; Cardiac toxicity

About this article
Title

Cardiotoxicity of radiation therapy in esophageal cancer

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 25, No 3 (2020)

Pages

318-322

Published online

2020-05-01

DOI

10.1016/j.rpor.2020.02.005

Bibliographic record

Rep Pract Oncol Radiother 2020;25(3):318-322.

Keywords

Esophageal cancer
Radiation therapy
Cardiac toxicity

Authors

Milan Vošmik
Miroslav Hodek
David Buka
Petra Sýkorová
Jakub Grepl
Petr Paluska
Simona Paulíková
Igor Sirák

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