open access

Vol 25, No 3 (2020)
Original research articles
Published online: 2020-05-01
Submitted: 2019-10-01
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A prospective observational study to analyse the influence of bladder and rectal volume changes on prostate radiotherapy using IMRT

Ramesh Arya, Harsh Goyal, Ayush Naik, Om Prakash Gurjar
DOI: 10.1016/j.rpor.2020.03.004
·
Rep Pract Oncol Radiother 2020;25(3):312-317.

open access

Vol 25, No 3 (2020)
Original research articles
Published online: 2020-05-01
Submitted: 2019-10-01

Abstract

Aim

To analyse the interfractional bladder and rectal volume changes and the influence on prostate position.

Background

Interfractional displacement of prostate due to variation in bladder and rectal volume is usual. It is only rational to study the bladder and rectal volume changes and their effects on prostate position during intensity modulated radiotherapy of prostate cancer.

Materials and Methods

A prospective study was conducted on twenty patients with localized prostate cancer during the first phase of radiotherapy, where 50 gray in 25 fractions was delivered by the IMRT technique with daily cone beam computed tomography Bladder and rectum volumes were delineated on CBCT images and their volumes were noted. Prostate position was noted on each set of CBCT images with respect to specific reference points defined on the ileum and coccyx, and daily prostate displacement was noted.

Results

Mean setup errors in vertical, longitudinal and lateral directions were noted as 1.49, 0.498 and 0.17 cm, respectively. Mean change in bladder and rectal volumes in daily CBCT images with respect to that on the first day CT images was noted as 101.94 and 10.22, respectively. Mean lateral and vertical displacement in prostate position was noted as 0.53 and 0.49 cm respectively. No considerable changes in dosimetric parameters were observed because of bladder and rectal volume changes.

Conclusions

Daily CBCT should be done for accurate treatment delivery by the IMRT technique for prostate radiotherapy as prostate shifts physiologically with changes in rectal and bladder volumes.

Abstract

Aim

To analyse the interfractional bladder and rectal volume changes and the influence on prostate position.

Background

Interfractional displacement of prostate due to variation in bladder and rectal volume is usual. It is only rational to study the bladder and rectal volume changes and their effects on prostate position during intensity modulated radiotherapy of prostate cancer.

Materials and Methods

A prospective study was conducted on twenty patients with localized prostate cancer during the first phase of radiotherapy, where 50 gray in 25 fractions was delivered by the IMRT technique with daily cone beam computed tomography Bladder and rectum volumes were delineated on CBCT images and their volumes were noted. Prostate position was noted on each set of CBCT images with respect to specific reference points defined on the ileum and coccyx, and daily prostate displacement was noted.

Results

Mean setup errors in vertical, longitudinal and lateral directions were noted as 1.49, 0.498 and 0.17 cm, respectively. Mean change in bladder and rectal volumes in daily CBCT images with respect to that on the first day CT images was noted as 101.94 and 10.22, respectively. Mean lateral and vertical displacement in prostate position was noted as 0.53 and 0.49 cm respectively. No considerable changes in dosimetric parameters were observed because of bladder and rectal volume changes.

Conclusions

Daily CBCT should be done for accurate treatment delivery by the IMRT technique for prostate radiotherapy as prostate shifts physiologically with changes in rectal and bladder volumes.

Get Citation

Keywords

Cone beam computed tomography; Intensity modulated radiotherapy; Prostate displacement

About this article
Title

A prospective observational study to analyse the influence of bladder and rectal volume changes on prostate radiotherapy using IMRT

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 25, No 3 (2020)

Pages

312-317

Published online

2020-05-01

DOI

10.1016/j.rpor.2020.03.004

Bibliographic record

Rep Pract Oncol Radiother 2020;25(3):312-317.

Keywords

Cone beam computed tomography
Intensity modulated radiotherapy
Prostate displacement

Authors

Ramesh Arya
Harsh Goyal
Ayush Naik
Om Prakash Gurjar

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