open access

Vol 25, No 1 (2020)
Reviews
Published online: 2020-01-01
Submitted: 2019-08-24
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Appropriate endpoints for stereotactic body radiotherapy for bone metastasis: Classification into five treatment groups

Kei Ito, Naoki Nakamura, Takuya Shimizuguchi, Hiroaki Ogawa, Katsuyuki Karasawa
DOI: 10.1016/j.rpor.2019.12.018
·
Rep Pract Oncol Radiother 2020;25(1):150-153.

open access

Vol 25, No 1 (2020)
Reviews
Published online: 2020-01-01
Submitted: 2019-08-24

Abstract

Treatment of bone metastasis using stereotactic body radiotherapy (SBRT) is being widely used in clinical practice. The reported clinical advantages of SBRT include high pain and local control rates, high response rates against bone metastasis from radio-resistant tumors, and safe re-irradiations. Although most reports in the literature use local control as the primary treatment endpoint, this endpoint is not appropriate because local control does not relate directly to patient benefit. Herein, we proposed five pathophysiology-based patient groups, as well as appropriate endpoints for each group.

Abstract

Treatment of bone metastasis using stereotactic body radiotherapy (SBRT) is being widely used in clinical practice. The reported clinical advantages of SBRT include high pain and local control rates, high response rates against bone metastasis from radio-resistant tumors, and safe re-irradiations. Although most reports in the literature use local control as the primary treatment endpoint, this endpoint is not appropriate because local control does not relate directly to patient benefit. Herein, we proposed five pathophysiology-based patient groups, as well as appropriate endpoints for each group.

Get Citation

Keywords

SBRT; Spine and non-spine bone metastasis; Endpoints; Treatment purpose

About this article
Title

Appropriate endpoints for stereotactic body radiotherapy for bone metastasis: Classification into five treatment groups

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 25, No 1 (2020)

Pages

150-153

Published online

2020-01-01

DOI

10.1016/j.rpor.2019.12.018

Bibliographic record

Rep Pract Oncol Radiother 2020;25(1):150-153.

Keywords

SBRT
Spine and non-spine bone metastasis
Endpoints
Treatment purpose

Authors

Kei Ito
Naoki Nakamura
Takuya Shimizuguchi
Hiroaki Ogawa
Katsuyuki Karasawa

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