open access

Vol 25, No 1 (2020)
Original research articles
Published online: 2020-01-01
Submitted: 2019-08-07
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Voluntary breath-hold reduces dose to organs at risk in radiotherapy of left-sided breast cancer

María Adela Poitevin-Chacón, Rubí Ramos-Prudencio, José Alfonso Rumoroso-García, Alejandro Rodríguez-Laguna, Julio Cesar Martínez-Robledo
DOI: 10.1016/j.rpor.2019.12.016
·
Rep Pract Oncol Radiother 2020;25(1):104-108.

open access

Vol 25, No 1 (2020)
Original research articles
Published online: 2020-01-01
Submitted: 2019-08-07

Abstract

Aim

To compare the dose to organs at risk with free breathing (FB) or voluntary breath-hold (VBH) during radiotherapy of patients with left sided breast cancer.

Background

Radiotherapy reduces the risk of breast-cancer-specific mortality but the effects on other organs increase non-cancer-specific mortality. Radiation exposure to the heart, in particular in patients with left sided breast cancer, can be reduced by breath hold methods that increase the distance between the heart and the radiation field.

Materials and Methods

Three-dimensional conformal radiotherapy (3D-CRT) dose plans for the left breast and organs at risk including the heart, left anterior descending coronary artery (LAD) and ipsilateral lung were compared with FB and VBH in ten patients with left sided breast cancer.

Results

The mean doses to the heart and LAD were reduced by 50.4 % (p<0.001) and 58.8 % (p=0.006), respectively, in VBH relative to FB. The mean dose to the ipsilateral lung was reduced by 13.8 % (p=0.11) in VBH relative to FB. The planning target volume (PTV) coverage was at least 95 % in both FB and VBH (p=0.78).

Conclusion

The VBH technique significantly reduces the dose to organs at risk in 3D-CRT treatment plans of left sided breast cancer.

Abstract

Aim

To compare the dose to organs at risk with free breathing (FB) or voluntary breath-hold (VBH) during radiotherapy of patients with left sided breast cancer.

Background

Radiotherapy reduces the risk of breast-cancer-specific mortality but the effects on other organs increase non-cancer-specific mortality. Radiation exposure to the heart, in particular in patients with left sided breast cancer, can be reduced by breath hold methods that increase the distance between the heart and the radiation field.

Materials and Methods

Three-dimensional conformal radiotherapy (3D-CRT) dose plans for the left breast and organs at risk including the heart, left anterior descending coronary artery (LAD) and ipsilateral lung were compared with FB and VBH in ten patients with left sided breast cancer.

Results

The mean doses to the heart and LAD were reduced by 50.4 % (p<0.001) and 58.8 % (p=0.006), respectively, in VBH relative to FB. The mean dose to the ipsilateral lung was reduced by 13.8 % (p=0.11) in VBH relative to FB. The planning target volume (PTV) coverage was at least 95 % in both FB and VBH (p=0.78).

Conclusion

The VBH technique significantly reduces the dose to organs at risk in 3D-CRT treatment plans of left sided breast cancer.

Get Citation

Keywords

Voluntary breath-hold; Cardiac dosimetry; Radiotherapy; Breast cancer

About this article
Title

Voluntary breath-hold reduces dose to organs at risk in radiotherapy of left-sided breast cancer

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 25, No 1 (2020)

Pages

104-108

Published online

2020-01-01

DOI

10.1016/j.rpor.2019.12.016

Bibliographic record

Rep Pract Oncol Radiother 2020;25(1):104-108.

Keywords

Voluntary breath-hold
Cardiac dosimetry
Radiotherapy
Breast cancer

Authors

María Adela Poitevin-Chacón
Rubí Ramos-Prudencio
José Alfonso Rumoroso-García
Alejandro Rodríguez-Laguna
Julio Cesar Martínez-Robledo

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