open access

Vol 24, No 5 (2019)
Original research articles
Published online: 2019-09-01
Submitted: 2018-10-16
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The incidence of inflammation among patients suffering from cervix cancer with positive beta haemolytic streptococci cultures from genital tract

Zefiryn Cybulski, Bartosz Urbański, Alicja Grabiec, Zofia Talaga, Michał Pawlak, Żaneta Wareńczak-Florczak, Andrzej Roszak
DOI: 10.1016/j.rpor.2019.07.004
·
Rep Pract Oncol Radiother 2019;24(5):428-431.

open access

Vol 24, No 5 (2019)
Original research articles
Published online: 2019-09-01
Submitted: 2018-10-16

Abstract

Aim

The main goal of this investigation was to evaluate the influence of positive beta haemolytic streptococci culture from the genital tract on patients receiving radiation therapy who suffer from cervical cancer. The other aim was to observe radiation therapy complications.

Background

Group B streptococci (GBS), group C streptococci (GCS) and group G streptococci (GGS) have been described as frequent invasive pathogens in elderly patients, often in association with underlying medical conditions including immunodeficiency and cancer.

Materials and methods

In the years 2006–2015, vaginal swabs from 452 patients were examined. A total of 118 women with positive beta haemolytic streptococci (BHS) groups A, B, C, F, G cultures were analysed, of whom 111 were diagnosed with cervix cancer of IB to IVA degree according to the FIGO 1988 clinical classification.

Results

Of the 452 patients suffering from cervix cancer 26.1% were positive for A, B, C, F or G group BHS isolated from the genital tract. All of the 114 examined strains were sensitive to beta-lactam antibiotics. The antimicrobials for which resistance was noted were erythromycin, clindamycin, ciprofloxacin and tetracycline.

Conclusions

Positive cultures of BHS from the genital tract were demonstrated to occur in patients with cervix cancer. Complications were found during radiotherapy in 30 (27%) of these patients, including 20 (18%) patients suffering from clinical symptoms of inflammation. When beta-lactam antibiotics are not recommended because of allergy, sensitivity tests to other drugs are necessary.

Abstract

Aim

The main goal of this investigation was to evaluate the influence of positive beta haemolytic streptococci culture from the genital tract on patients receiving radiation therapy who suffer from cervical cancer. The other aim was to observe radiation therapy complications.

Background

Group B streptococci (GBS), group C streptococci (GCS) and group G streptococci (GGS) have been described as frequent invasive pathogens in elderly patients, often in association with underlying medical conditions including immunodeficiency and cancer.

Materials and methods

In the years 2006–2015, vaginal swabs from 452 patients were examined. A total of 118 women with positive beta haemolytic streptococci (BHS) groups A, B, C, F, G cultures were analysed, of whom 111 were diagnosed with cervix cancer of IB to IVA degree according to the FIGO 1988 clinical classification.

Results

Of the 452 patients suffering from cervix cancer 26.1% were positive for A, B, C, F or G group BHS isolated from the genital tract. All of the 114 examined strains were sensitive to beta-lactam antibiotics. The antimicrobials for which resistance was noted were erythromycin, clindamycin, ciprofloxacin and tetracycline.

Conclusions

Positive cultures of BHS from the genital tract were demonstrated to occur in patients with cervix cancer. Complications were found during radiotherapy in 30 (27%) of these patients, including 20 (18%) patients suffering from clinical symptoms of inflammation. When beta-lactam antibiotics are not recommended because of allergy, sensitivity tests to other drugs are necessary.

Get Citation

Keywords

Beta haemolytic streptococci; Cervix cancer patients; Radiation therapy complications

About this article
Title

The incidence of inflammation among patients suffering from cervix cancer with positive beta haemolytic streptococci cultures from genital tract

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 24, No 5 (2019)

Pages

428-431

Published online

2019-09-01

DOI

10.1016/j.rpor.2019.07.004

Bibliographic record

Rep Pract Oncol Radiother 2019;24(5):428-431.

Keywords

Beta haemolytic streptococci
Cervix cancer patients
Radiation therapy complications

Authors

Zefiryn Cybulski
Bartosz Urbański
Alicja Grabiec
Zofia Talaga
Michał Pawlak
Żaneta Wareńczak-Florczak
Andrzej Roszak

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