open access

Vol 24, No 4 (2019)
Original research articles
Published online: 2019-07-01
Submitted: 2018-03-16
Get Citation

Patients’ view of the differences in topical creams for radiation dermatitis prevention. A pilot study of cosmetic properties

Sebastia Sabater, Rafael Leon, Cesar Esteban, Jose Luis Añon, Meritxell Arenas
DOI: 10.1016/j.rpor.2019.03.006
·
Rep Pract Oncol Radiother 2019;24(4):347-354.

open access

Vol 24, No 4 (2019)
Original research articles
Published online: 2019-07-01
Submitted: 2018-03-16

Abstract

Aim

To investigate the feasibility of including patients’ reports on the cosmetic properties of topical formulations for acute radiation dermatitis (ARD).

Background

No topical agent tested for acute radiation dermatitis (ARD) has proven to be better than any other, all achieving similar objective outcomes. No clear guidelines have therefore been established in clinics. Because the vehicle for such creams has shown to be an important factor in patient adherence to treatments in other dermatological diseases, patients’ opinions are evaluated.

Material and methods

Seventy breast cancer patients referred for postoperative radiotherapy after conservative surgery were enrolled. Patients were assigned to use one of the 7 topical agents that are most-commonly used in the prevention of ARD. Patients’ reports were assessed using continuous visual analogue scales (VAS), objective signs and symptoms produced by ARD, and were rated using the RTOG and RISRAS scales.

Results

The creams tested differed in their cosmetic properties significantly (p=0.044). The performance of the agent, their absorption and any residue left over were also significantly different (p=0.022, 0.014 and 0.02, respectively).

Conclusions

Topical agents for preventive ARD are reported by patients to show different cosmetic properties. Cosmetic properties are important when choosing topical agents for ARD prevention. Recommending those with better cosmetic profiles would improve patient adherence to treatments.

Abstract

Aim

To investigate the feasibility of including patients’ reports on the cosmetic properties of topical formulations for acute radiation dermatitis (ARD).

Background

No topical agent tested for acute radiation dermatitis (ARD) has proven to be better than any other, all achieving similar objective outcomes. No clear guidelines have therefore been established in clinics. Because the vehicle for such creams has shown to be an important factor in patient adherence to treatments in other dermatological diseases, patients’ opinions are evaluated.

Material and methods

Seventy breast cancer patients referred for postoperative radiotherapy after conservative surgery were enrolled. Patients were assigned to use one of the 7 topical agents that are most-commonly used in the prevention of ARD. Patients’ reports were assessed using continuous visual analogue scales (VAS), objective signs and symptoms produced by ARD, and were rated using the RTOG and RISRAS scales.

Results

The creams tested differed in their cosmetic properties significantly (p=0.044). The performance of the agent, their absorption and any residue left over were also significantly different (p=0.022, 0.014 and 0.02, respectively).

Conclusions

Topical agents for preventive ARD are reported by patients to show different cosmetic properties. Cosmetic properties are important when choosing topical agents for ARD prevention. Recommending those with better cosmetic profiles would improve patient adherence to treatments.

Get Citation

Keywords

ARD; CTCAE; QoL; RISRAS; RT; RTOG; STAT; Radiotherapy; Radiation dermatitis; Cosmetic properties; Patient-reported outcomes; RTOG; RISRAS

About this article
Title

Patients’ view of the differences in topical creams for radiation dermatitis prevention. A pilot study of cosmetic properties

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 24, No 4 (2019)

Pages

347-354

Published online

2019-07-01

DOI

10.1016/j.rpor.2019.03.006

Bibliographic record

Rep Pract Oncol Radiother 2019;24(4):347-354.

Keywords

ARD
CTCAE
QoL
RISRAS
RT
RTOG
STAT
Radiotherapy
Radiation dermatitis
Cosmetic properties
Patient-reported outcomes
RTOG
RISRAS

Authors

Sebastia Sabater
Rafael Leon
Cesar Esteban
Jose Luis Añon
Meritxell Arenas

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk, Poland
tel.:+48 58 320 94 94, fax:+48 58 320 94 60, e-mail: journals@viamedica.pl