open access
Problems and solutions in IGRT for cervical cancer
open access
Abstract
The contribution of Image-guided Radiotherapy (IGRT) to modern radiotherapy is undeniable, being the way to bring into daily practice the dosimetric benefits of Intensity-Modulated Radiotherapy (IMRT). Organ and target motion is constant and unpredictable at the pelvis, thus posing a challenge to the safe execution of IMRT. There are potential benefits of IMRT in the radical treatment of cervical cancer patients, both in terms of dose escalation and decrease of toxicity. But it is essential to find IGRT solutions to control the aspects that can lead to geographic miss targeting or organs at risk (OAR) overdose. This review seeks to describe the problems and possible solutions in the clinical implementation of IMRT/IGRT protocols to treat intact cervical cancer patients.
Abstract
The contribution of Image-guided Radiotherapy (IGRT) to modern radiotherapy is undeniable, being the way to bring into daily practice the dosimetric benefits of Intensity-Modulated Radiotherapy (IMRT). Organ and target motion is constant and unpredictable at the pelvis, thus posing a challenge to the safe execution of IMRT. There are potential benefits of IMRT in the radical treatment of cervical cancer patients, both in terms of dose escalation and decrease of toxicity. But it is essential to find IGRT solutions to control the aspects that can lead to geographic miss targeting or organs at risk (OAR) overdose. This review seeks to describe the problems and possible solutions in the clinical implementation of IMRT/IGRT protocols to treat intact cervical cancer patients.
Keywords
Cervical cancer treatment; Pelvic IGRT; Pelvic IMRT; CBCT in cervical cancer; Image guidance; Organ motion
About this articleTitle
Problems and solutions in IGRT for cervical cancer
Journal
Reports of Practical Oncology and Radiotherapy
Issue
Pages
517-527
Published online
2018-11-01
DOI
10.1016/j.rpor.2018.05.002
Bibliographic record
Rep Pract Oncol Radiother 2018;23(6):517-527.
Keywords
Cervical cancer treatment
Pelvic IGRT
Pelvic IMRT
CBCT in cervical cancer
Image guidance
Organ motion
Authors
Iván Ríos
Ilse Vásquez
Elsa Cuervo
Óscar Garzón
Johnny Burbano