open access

Vol 23, No 6 (2018)
Special Issue Papers
Published online: 2018-11-01
Submitted: 2017-11-18
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Present status of sentinel lymph node biopsy in cervical cancer

Ariel Gustavo Glickman, Sergio Valdes, Blanca Gil-Ibañez, Pilar Paredes, Karen Sttephannía Cortés, Aureli Angel Torné Blade
DOI: 10.1016/j.rpor.2018.04.004
·
Rep Pract Oncol Radiother 2018;23(6):495-502.

open access

Vol 23, No 6 (2018)
Special Issue Papers
Published online: 2018-11-01
Submitted: 2017-11-18

Abstract

Cervical cancer is the fourth most common cancer in women, and seventh overall. This disease represents a medical, economic and social burden. In early FIGO stage patients (IA, IB1 and IIA1), nodal involvement is the most important prognostic factor. Imaging evaluation of nodal metastasis is of limited value. In order to determine lymph node involvement, allow loco-regional control of the disease, define the need for adjuvant radiotherapy and improve survival, standard surgery for early disease is radical hysterectomy with systematic pelvic lymphadenectomy. However, this surgical treatment has risks and complications: longer operative time, larger blood loss, neurovascular or ureteral injury, lower-limb lymphedema, symptomatic lymphocysts, hydronephrosis. A method that allows to define the presence of regional metastasis with less morbidity and equal or greater precision is particularly relevant. The use of the sentinel lymph node biopsy is intended to reach that purpose. The present study reviews recent literature on the role of sentinel lymph node biopsy in cervical cancer, analyzing its indications and contraindications, injection and detection techniques, tracers used, surgical and pathological approaches and its applicability in up-to-date clinical practice.

Abstract

Cervical cancer is the fourth most common cancer in women, and seventh overall. This disease represents a medical, economic and social burden. In early FIGO stage patients (IA, IB1 and IIA1), nodal involvement is the most important prognostic factor. Imaging evaluation of nodal metastasis is of limited value. In order to determine lymph node involvement, allow loco-regional control of the disease, define the need for adjuvant radiotherapy and improve survival, standard surgery for early disease is radical hysterectomy with systematic pelvic lymphadenectomy. However, this surgical treatment has risks and complications: longer operative time, larger blood loss, neurovascular or ureteral injury, lower-limb lymphedema, symptomatic lymphocysts, hydronephrosis. A method that allows to define the presence of regional metastasis with less morbidity and equal or greater precision is particularly relevant. The use of the sentinel lymph node biopsy is intended to reach that purpose. The present study reviews recent literature on the role of sentinel lymph node biopsy in cervical cancer, analyzing its indications and contraindications, injection and detection techniques, tracers used, surgical and pathological approaches and its applicability in up-to-date clinical practice.

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Keywords

Sentinel lymph node biopsy; Cervical cancer; Injection techniques and tracers; Detection rate; Sensitivity; Clinical relevance

About this article
Title

Present status of sentinel lymph node biopsy in cervical cancer

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 23, No 6 (2018)

Pages

495-502

Published online

2018-11-01

DOI

10.1016/j.rpor.2018.04.004

Bibliographic record

Rep Pract Oncol Radiother 2018;23(6):495-502.

Keywords

Sentinel lymph node biopsy
Cervical cancer
Injection techniques and tracers
Detection rate
Sensitivity
Clinical relevance

Authors

Ariel Gustavo Glickman
Sergio Valdes
Blanca Gil-Ibañez
Pilar Paredes
Karen Sttephannía Cortés
Aureli Angel Torné Blade

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