open access

Vol 23, No 5 (2018)
Original research articles
Published online: 2018-09-01
Submitted: 2018-01-03
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Intrafraction esophageal motion in patients with clinical T1N0 esophageal cancer

Shuhei Sekii, Yoshinori Ito, Ken Harada, Mayuka Kitaguchi, Kana Takahashi, Koji Inaba, Naoya Murakami, Hiroshi Igaki, Ryohei Sasaki, Jun Itami
DOI: 10.1016/j.rpor.2018.07.013
·
Rep Pract Oncol Radiother 2018;23(5):398-401.

open access

Vol 23, No 5 (2018)
Original research articles
Published online: 2018-09-01
Submitted: 2018-01-03

Abstract

Aim

To investigate the intrafraction movement of the esophagus using fiducial markers.

Background

Studies on intrafraction esophageal motion using the fiducial markers are scarce.

Materials and methods

We retrospectively analyzed patients with clinical T1N0 esophageal cancer who had received fiducial markers at our hospital between July 2007 and December 2013. Real-Time Position Management System to track the patient's respiration was used, and each patient underwent three-dimensional computed tomography of the resting expiratory and inspiratory level. We used the center of the marker to calculate the distance between the expiratory and inspiratory breath-holds, which were measured with the radiotherapy treatment planning system in three directions: left–right (LR), superior–inferior (SI), and anterior–posterior (AP). The movements at each site were compared with the Kruskal–Wallis analysis and Wilcoxon rank sum test with a Bonferroni correction.

Results

A total of 101 patients with 201 fiducial markers were included. The upper, middle and lower thoracic positions had 40, 77, and 84 markers, respectively. The mean absolute magnitudes of the shifts (standard deviation) were 0.18 (0.19) cm, 0.68 (0.46) cm, and 0.24 (0.24) cm in the LR, SI, and AP directions, respectively. From the cumulative frequency distribution, we assumed that 0.35 cm LR, 0.8 cm SI, and 0.3 cm AP in the upper; 0.5 cm LR, 1.55 cm SI, and 0.55 cm AP in the middle; and 0.75 cm LR, 1.9 cm SI, and 0.95 cm AP in the lower thoracic esophagus covered 95% of the cases.

Conclusions

The internal margin based on the site of esophagus was estimated.

Abstract

Aim

To investigate the intrafraction movement of the esophagus using fiducial markers.

Background

Studies on intrafraction esophageal motion using the fiducial markers are scarce.

Materials and methods

We retrospectively analyzed patients with clinical T1N0 esophageal cancer who had received fiducial markers at our hospital between July 2007 and December 2013. Real-Time Position Management System to track the patient's respiration was used, and each patient underwent three-dimensional computed tomography of the resting expiratory and inspiratory level. We used the center of the marker to calculate the distance between the expiratory and inspiratory breath-holds, which were measured with the radiotherapy treatment planning system in three directions: left–right (LR), superior–inferior (SI), and anterior–posterior (AP). The movements at each site were compared with the Kruskal–Wallis analysis and Wilcoxon rank sum test with a Bonferroni correction.

Results

A total of 101 patients with 201 fiducial markers were included. The upper, middle and lower thoracic positions had 40, 77, and 84 markers, respectively. The mean absolute magnitudes of the shifts (standard deviation) were 0.18 (0.19) cm, 0.68 (0.46) cm, and 0.24 (0.24) cm in the LR, SI, and AP directions, respectively. From the cumulative frequency distribution, we assumed that 0.35 cm LR, 0.8 cm SI, and 0.3 cm AP in the upper; 0.5 cm LR, 1.55 cm SI, and 0.55 cm AP in the middle; and 0.75 cm LR, 1.9 cm SI, and 0.95 cm AP in the lower thoracic esophagus covered 95% of the cases.

Conclusions

The internal margin based on the site of esophagus was estimated.

Get Citation

Keywords

Intrafraction motion; Esophageal cancer; Gastrointestinal cancer; Fiducial marker

About this article
Title

Intrafraction esophageal motion in patients with clinical T1N0 esophageal cancer

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 23, No 5 (2018)

Pages

398-401

Published online

2018-09-01

DOI

10.1016/j.rpor.2018.07.013

Bibliographic record

Rep Pract Oncol Radiother 2018;23(5):398-401.

Keywords

Intrafraction motion
Esophageal cancer
Gastrointestinal cancer
Fiducial marker

Authors

Shuhei Sekii
Yoshinori Ito
Ken Harada
Mayuka Kitaguchi
Kana Takahashi
Koji Inaba
Naoya Murakami
Hiroshi Igaki
Ryohei Sasaki
Jun Itami

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