open access
Intensity-modulated radiation therapy and volumetric modulated arc therapy versus conventional conformal techniques at high energy: Dose assessment and impact on second primary cancer in the out-of-field region
open access
Abstract
The aim of this work was to estimate peripheral neutron and photon doses associated with the conventional 3D conformal radiotherapy techniques in comparison to modern ones such as Intensity modulated radiation therapy and volumetric modulated arc therapy. Assessment in terms of second cancer incidence ought to peripheral doses was also considered. For that, a dosimetric methodology proposed by the authors has been applied beyond the region where there is no CT information and, thus, treatment planning systems do not calculate and where, nonetheless, about one third of second primary cancers occurs.
Abstract
The aim of this work was to estimate peripheral neutron and photon doses associated with the conventional 3D conformal radiotherapy techniques in comparison to modern ones such as Intensity modulated radiation therapy and volumetric modulated arc therapy. Assessment in terms of second cancer incidence ought to peripheral doses was also considered. For that, a dosimetric methodology proposed by the authors has been applied beyond the region where there is no CT information and, thus, treatment planning systems do not calculate and where, nonetheless, about one third of second primary cancers occurs.
Keywords
Second primary cancer; Peripheral doses in radiotherapy
About this articleTitle
Intensity-modulated radiation therapy and volumetric modulated arc therapy versus conventional conformal techniques at high energy: Dose assessment and impact on second primary cancer in the out-of-field region
Journal
Reports of Practical Oncology and Radiotherapy
Issue
Pages
251-259
Published online
2018-07-01
DOI
10.1016/j.rpor.2018.04.008
Bibliographic record
Rep Pract Oncol Radiother 2018;23(4):251-259.
Keywords
Second primary cancer
Peripheral doses in radiotherapy
Authors
Beatriz Sánchez-Nieto
Maria Romero-Expósito
José Antonio Terrón
Leticia Irazola
Marta Paiusco
Elisabetta Cagni
Caterina Ghetti
Silvano Filice
Francisco Sánchez-Doblado