open access

Vol 22, No 4 (2017)
Original research articles
Published online: 2017-07-01
Submitted: 2016-11-05
Get Citation

Evaluating the performance of TG-43 protocol in esophageal HDR brachytherapy viewpoint to trachea inhomogeneity

Seyed Mohsen Hosseini Daghigh, Hamid Reza Baghani, Seyed Mahmoud Aghamiri, Seyed Rabi Mahdavi
DOI: 10.1016/j.rpor.2017.04.001
·
Rep Pract Oncol Radiother 2017;22(4):284-289.

open access

Vol 22, No 4 (2017)
Original research articles
Published online: 2017-07-01
Submitted: 2016-11-05

Abstract

Aim

The aim of this study is to evaluate the effect of air within trachea on dose calculations of esophageal HDR brachytherapy treatment planning.

Background

Dose calculations in esophageal HDR brachytherapy treatment planning systems are greatly based on TG-43 protocol which in all materials are considered to be water equivalent.

Materials and methods

A cylindrical PMMA phantom with a tube in the center (neck equivalent phantom) accompanied by Flexitron HDR brachytherapy system was used in this study. Brachytherapy applicators with various diameters were placed inside the esophageal tube and EDR2 film was used for dosimetry. The absorbed dose by reference point of esophageal HDR brachytherapy and anterior wall of trachea were measured and compared with those calculated by Flexiplan treatment planning system.

Results

Based on the performed statistical analysis (t-test) with 95% confidence level (t-value >1.96), there was a meaningful difference between the results of film dosimetry and treatment planning at all of the points understudy.

Conclusion

The meaningful difference between the results of film dosimetry and treatment planning indicates that the trachea inhomogeneity has a considerable effect on dose calculations of Flexiplan treatment planning software featuring the TG-43 dose calculation algorithm. This mismatch can affect the accuracy of performed treatment plan and irradiation.

Abstract

Aim

The aim of this study is to evaluate the effect of air within trachea on dose calculations of esophageal HDR brachytherapy treatment planning.

Background

Dose calculations in esophageal HDR brachytherapy treatment planning systems are greatly based on TG-43 protocol which in all materials are considered to be water equivalent.

Materials and methods

A cylindrical PMMA phantom with a tube in the center (neck equivalent phantom) accompanied by Flexitron HDR brachytherapy system was used in this study. Brachytherapy applicators with various diameters were placed inside the esophageal tube and EDR2 film was used for dosimetry. The absorbed dose by reference point of esophageal HDR brachytherapy and anterior wall of trachea were measured and compared with those calculated by Flexiplan treatment planning system.

Results

Based on the performed statistical analysis (t-test) with 95% confidence level (t-value >1.96), there was a meaningful difference between the results of film dosimetry and treatment planning at all of the points understudy.

Conclusion

The meaningful difference between the results of film dosimetry and treatment planning indicates that the trachea inhomogeneity has a considerable effect on dose calculations of Flexiplan treatment planning software featuring the TG-43 dose calculation algorithm. This mismatch can affect the accuracy of performed treatment plan and irradiation.

Get Citation

Keywords

Esophageal HDR brachytherapy; Trachea inhomogeneity; TG-43 protocol; Treatment planning; Film dosimetry

About this article
Title

Evaluating the performance of TG-43 protocol in esophageal HDR brachytherapy viewpoint to trachea inhomogeneity

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 22, No 4 (2017)

Pages

284-289

Published online

2017-07-01

DOI

10.1016/j.rpor.2017.04.001

Bibliographic record

Rep Pract Oncol Radiother 2017;22(4):284-289.

Keywords

Esophageal HDR brachytherapy
Trachea inhomogeneity
TG-43 protocol
Treatment planning
Film dosimetry

Authors

Seyed Mohsen Hosseini Daghigh
Hamid Reza Baghani
Seyed Mahmoud Aghamiri
Seyed Rabi Mahdavi

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk, Poland
tel.:+48 58 320 94 94, fax:+48 58 320 94 60, e-mail: journals@viamedica.pl