open access

Vol 22, No 1 (2017)
Original research articles
Published online: 2017-01-01
Submitted: 2015-09-30
Get Citation

Products based on olive oil, betaine, and xylitol in the post-radiotherapy xerostomia

Margarita Martín, Alicia Marín, Mario López, Olga Liñán, Felipe Alvarenga, David Büchser, Laura Cerezo
DOI: 10.1016/j.rpor.2016.09.008
·
Rep Pract Oncol Radiother 2017;22(1):71-76.

open access

Vol 22, No 1 (2017)
Original research articles
Published online: 2017-01-01
Submitted: 2015-09-30

Abstract

Aim

The objective of this study was determining if the use of products based in olive oil, betaine and xylitol are efficacious to decrease the impact of the dry mouth in the quality of life of the patients with xerostomia due to radiotherapy treatment.

Background

Following therapeutic irradiation of the head and neck, patients with profound xerostomia have complaints associated with oral dryness, speech, and taste. There is no strong evidence that any topical therapy is effective for relieving the symptom of dry mouth.

Material and methods

40 patients who had been treated with radiotherapy for head and neck carcinoma and reported symptoms of dry mouth were included in the study. A xerostomia-related quality of life questionnaire, visual analogue scale questionnaire for subjective assessment of salivary dysfunction and salivary flow were reported before and 15 days after the use of topical products based on olive oil, betaina and xylitol.

Results

The four primary quality of life areas demonstrated significantly greater improvement after the use of topical products and all eight VAS items had favourable changes. The reduction of symptoms was statistically significant in 7 of the 8 items. After the use of the products, there were improvements in salivary flow in 45%.

Conclusions

The use of products based on olive oil, betaine and xylitol, shaped like collutory, toothpaste, gel and spray significantly improved most symptoms and the quality of life limitations produced by dry mouth in patients treated with radiotherapy.

Abstract

Aim

The objective of this study was determining if the use of products based in olive oil, betaine and xylitol are efficacious to decrease the impact of the dry mouth in the quality of life of the patients with xerostomia due to radiotherapy treatment.

Background

Following therapeutic irradiation of the head and neck, patients with profound xerostomia have complaints associated with oral dryness, speech, and taste. There is no strong evidence that any topical therapy is effective for relieving the symptom of dry mouth.

Material and methods

40 patients who had been treated with radiotherapy for head and neck carcinoma and reported symptoms of dry mouth were included in the study. A xerostomia-related quality of life questionnaire, visual analogue scale questionnaire for subjective assessment of salivary dysfunction and salivary flow were reported before and 15 days after the use of topical products based on olive oil, betaina and xylitol.

Results

The four primary quality of life areas demonstrated significantly greater improvement after the use of topical products and all eight VAS items had favourable changes. The reduction of symptoms was statistically significant in 7 of the 8 items. After the use of the products, there were improvements in salivary flow in 45%.

Conclusions

The use of products based on olive oil, betaine and xylitol, shaped like collutory, toothpaste, gel and spray significantly improved most symptoms and the quality of life limitations produced by dry mouth in patients treated with radiotherapy.

Get Citation

Keywords

Head and neck neoplasms; Quality of life; Questionnaires; Visual analogue scale; Xerostomia

About this article
Title

Products based on olive oil, betaine, and xylitol in the post-radiotherapy xerostomia

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 22, No 1 (2017)

Pages

71-76

Published online

2017-01-01

DOI

10.1016/j.rpor.2016.09.008

Bibliographic record

Rep Pract Oncol Radiother 2017;22(1):71-76.

Keywords

Head and neck neoplasms
Quality of life
Questionnaires
Visual analogue scale
Xerostomia

Authors

Margarita Martín
Alicia Marín
Mario López
Olga Liñán
Felipe Alvarenga
David Büchser
Laura Cerezo

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk, Poland
tel.:+48 58 320 94 94, fax:+48 58 320 94 60, e-mail: journals@viamedica.pl