open access

Vol 21, No 4 (2016)
Special Issue Papers
Published online: 2016-07-01
Submitted: 2014-10-24
Get Citation

Temporal bone carcinoma: Classical prognostic variables revisited and modern clinico-pathological evidence

Elisabetta Zanoletti, Gino Marioni, Sebastiano Franchella, Sara Munari, Roberto Pareschi, Antonio Mazzoni, Alessandro Martini
DOI: 10.1016/j.rpor.2015.07.004
·
Rep Pract Oncol Radiother 2016;21(4):386-390.

open access

Vol 21, No 4 (2016)
Special Issue Papers
Published online: 2016-07-01
Submitted: 2014-10-24

Abstract

Aim

Prognostic factors, rational management, and the ongoing investigations regarding temporal bone squamous cell carcinoma (TBSCC) have been critically reviewed.

Background

TBSCC is an uncommon, aggressive malignancy. Although some progress has been made in treating this aggressive tumor, the prognosis in advanced cases remains poor.

Materials and methods

A systematic search of the literature for articles published between 2009 and October 2014 was performed using the PubMed ([[ce:inter-ref id="intr0005" xlink:href="http://www.pubmed.gov/"]]http://www.pubmed.gov) electronic database.

Results

Given the particular anatomical site of TBSCC, its prognosis is significantly influenced by any direct involvement of nearby structures. The extent of the primary tumor is generally considered one of the most important prognostic factors and it is frequently related to prognosis even more strongly than N stage. For TBSCC, biomarker investigations in surgical specimens are only just beginning to appear in the oncological literature.

Conclusion

Given the particular features of TBSCC, the sub-specialty of otologic oncology seems to be emerging as a defined area of practice involving multidisciplinary team comprising oto-neurosurgeons, head and neck surgeons, plastic surgeons, oncologists, radiotherapists, dedicated radiologists, and pathologists.

Abstract

Aim

Prognostic factors, rational management, and the ongoing investigations regarding temporal bone squamous cell carcinoma (TBSCC) have been critically reviewed.

Background

TBSCC is an uncommon, aggressive malignancy. Although some progress has been made in treating this aggressive tumor, the prognosis in advanced cases remains poor.

Materials and methods

A systematic search of the literature for articles published between 2009 and October 2014 was performed using the PubMed ([[ce:inter-ref id="intr0005" xlink:href="http://www.pubmed.gov/"]]http://www.pubmed.gov) electronic database.

Results

Given the particular anatomical site of TBSCC, its prognosis is significantly influenced by any direct involvement of nearby structures. The extent of the primary tumor is generally considered one of the most important prognostic factors and it is frequently related to prognosis even more strongly than N stage. For TBSCC, biomarker investigations in surgical specimens are only just beginning to appear in the oncological literature.

Conclusion

Given the particular features of TBSCC, the sub-specialty of otologic oncology seems to be emerging as a defined area of practice involving multidisciplinary team comprising oto-neurosurgeons, head and neck surgeons, plastic surgeons, oncologists, radiotherapists, dedicated radiologists, and pathologists.

Get Citation

Keywords

Temporal bone; Squamous cell carcinoma; Prognosis

About this article
Title

Temporal bone carcinoma: Classical prognostic variables revisited and modern clinico-pathological evidence

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 21, No 4 (2016)

Pages

386-390

Published online

2016-07-01

DOI

10.1016/j.rpor.2015.07.004

Bibliographic record

Rep Pract Oncol Radiother 2016;21(4):386-390.

Keywords

Temporal bone
Squamous cell carcinoma
Prognosis

Authors

Elisabetta Zanoletti
Gino Marioni
Sebastiano Franchella
Sara Munari
Roberto Pareschi
Antonio Mazzoni
Alessandro Martini

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk, Poland
tel.:+48 58 320 94 94, fax:+48 58 320 94 60, e-mail: journals@viamedica.pl