open access

Vol 21, No 4 (2016)
Special Issue Papers
Published online: 2016-07-01
Submitted: 2014-05-28
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Surgical management of skull base tumors

Leonardo Rangel-Castilla, Jonathan J. Russin, Robert F. Spetzler
DOI: 10.1016/j.rpor.2014.09.002
·
Rep Pract Oncol Radiother 2016;21(4):325-335.

open access

Vol 21, No 4 (2016)
Special Issue Papers
Published online: 2016-07-01
Submitted: 2014-05-28

Abstract

Aim

To present a review of the contemporary surgical management of skull base tumors.

Background

Over the last two decades, the treatment of skull base tumors has evolved from observation, to partial resection combined with other therapy modalities, to gross total resection and no adjuvant treatment with good surgical results and excellent clinical outcomes.

Materials and methods

The literature review of current surgical strategies and management of skull base tumors was performed and complemented with the experience of Barrow Neurological Institute.

Results

Skull base tumors include meningiomas, pituitary tumors, sellar/parasellar tumors, vestibular and trigeminal schwannomas, esthesioneuroblastomas, chordomas, chondrosarcomas, and metastases. Surgical approaches include the modified orbitozygomatic, pterional, middle fossa, retrosigmoid, far lateral craniotomy, midline suboccipital craniotomy, and a combination of these approaches. The selection of an appropriate surgical approach depends on the characteristics of the patient and the tumor, as well as the experience of the neurosurgeon.

Conclusion

Modern microsurgical techniques, diagnostic imaging, intraoperative neuronavigation, and endoscopic technology have remarkably changed the concept of skull base surgery. These refinements have extended the boundaries of tumor resection with minimal morbidity.

Abstract

Aim

To present a review of the contemporary surgical management of skull base tumors.

Background

Over the last two decades, the treatment of skull base tumors has evolved from observation, to partial resection combined with other therapy modalities, to gross total resection and no adjuvant treatment with good surgical results and excellent clinical outcomes.

Materials and methods

The literature review of current surgical strategies and management of skull base tumors was performed and complemented with the experience of Barrow Neurological Institute.

Results

Skull base tumors include meningiomas, pituitary tumors, sellar/parasellar tumors, vestibular and trigeminal schwannomas, esthesioneuroblastomas, chordomas, chondrosarcomas, and metastases. Surgical approaches include the modified orbitozygomatic, pterional, middle fossa, retrosigmoid, far lateral craniotomy, midline suboccipital craniotomy, and a combination of these approaches. The selection of an appropriate surgical approach depends on the characteristics of the patient and the tumor, as well as the experience of the neurosurgeon.

Conclusion

Modern microsurgical techniques, diagnostic imaging, intraoperative neuronavigation, and endoscopic technology have remarkably changed the concept of skull base surgery. These refinements have extended the boundaries of tumor resection with minimal morbidity.

Get Citation

Keywords

Skull base; Skull base surgery; Meningoma; Neuroma; Schwannoma

About this article
Title

Surgical management of skull base tumors

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 21, No 4 (2016)

Pages

325-335

Published online

2016-07-01

DOI

10.1016/j.rpor.2014.09.002

Bibliographic record

Rep Pract Oncol Radiother 2016;21(4):325-335.

Keywords

Skull base
Skull base surgery
Meningoma
Neuroma
Schwannoma

Authors

Leonardo Rangel-Castilla
Jonathan J. Russin
Robert F. Spetzler

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