open access
Pathologic aspects of skull base tumors
open access
Abstract
Skull base tumors form a highly heterogeneous group. As there are several structures in this anatomical site, a large number of different primary malignancies might develop, as well as a variety of secondary (metastatic) tumors. In this article, the most common malignancies are presented, along with a short histopathologic description. For some entities, an immunohistochemical profile is also given that should be helpful in proper diagnosis. As many pathologic diagnoses nowadays also include genetic studies, the most common genetic abnormalities in skull base tumors are presented.
Abstract
Skull base tumors form a highly heterogeneous group. As there are several structures in this anatomical site, a large number of different primary malignancies might develop, as well as a variety of secondary (metastatic) tumors. In this article, the most common malignancies are presented, along with a short histopathologic description. For some entities, an immunohistochemical profile is also given that should be helpful in proper diagnosis. As many pathologic diagnoses nowadays also include genetic studies, the most common genetic abnormalities in skull base tumors are presented.
Keywords
Skull base tumors; Histopathology; Malignant; Benign
About this articleTitle
Pathologic aspects of skull base tumors
Journal
Reports of Practical Oncology and Radiotherapy
Issue
Pages
288-303
Published online
2016-07-01
DOI
10.1016/j.rpor.2016.02.006
Bibliographic record
Rep Pract Oncol Radiother 2016;21(4):288-303.
Keywords
Skull base tumors
Histopathology
Malignant
Benign
Authors
Andrzej Marszałek
Łukasz Szylberg
Sławomir Wiśniewski