open access

Vol 21, No 1 (2016)
Published online: 2016-01-01
Submitted: 2015-06-03
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Vemurafenib and concomitant stereotactic radiation for the treatment of melanoma with spinal metastases: A case report

Dinu Stefan, Hosni Popotte, Andreea Raluca Stefan, Audrey Tesniere, Aurélie Tomaszewski, Paul Lesueur, Jean-Louis Habrand, Laurence Verneuil
DOI: 10.1016/j.rpor.2015.07.005
·
Rep Pract Oncol Radiother 2016;21(1):76-80.

open access

Vol 21, No 1 (2016)
Published online: 2016-01-01
Submitted: 2015-06-03

Abstract

A 56-year-old man with BRAFV600E melanoma and spinal metastases treated with vemurafenib and stereotactic radiation showed a partial response without neurological, skin or mucosal toxicity, 8 months after completion of this combination. This case suggests that stereotactic radiation spares normal tissues and might be safer than conventional fractionated radiation with vemurafenib.

Abstract

A 56-year-old man with BRAFV600E melanoma and spinal metastases treated with vemurafenib and stereotactic radiation showed a partial response without neurological, skin or mucosal toxicity, 8 months after completion of this combination. This case suggests that stereotactic radiation spares normal tissues and might be safer than conventional fractionated radiation with vemurafenib.

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Keywords

Vemurafenib; Stereotactic radiation; Melanoma metastasis

About this article
Title

Vemurafenib and concomitant stereotactic radiation for the treatment of melanoma with spinal metastases: A case report

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 21, No 1 (2016)

Pages

76-80

Published online

2016-01-01

DOI

10.1016/j.rpor.2015.07.005

Bibliographic record

Rep Pract Oncol Radiother 2016;21(1):76-80.

Keywords

Vemurafenib
Stereotactic radiation
Melanoma metastasis

Authors

Dinu Stefan
Hosni Popotte
Andreea Raluca Stefan
Audrey Tesniere
Aurélie Tomaszewski
Paul Lesueur
Jean-Louis Habrand
Laurence Verneuil

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