Vol 21, No 1 (2016)
Published online: 2016-01-01
Vemurafenib and concomitant stereotactic radiation for the treatment of melanoma with spinal metastases: A case report
DOI: 10.1016/j.rpor.2015.07.005
Rep Pract Oncol Radiother 2016;21(1):76-80.
Abstract
A 56-year-old man with BRAFV600E melanoma and spinal metastases treated with vemurafenib and stereotactic radiation showed a partial response without neurological, skin or mucosal toxicity, 8 months after completion of this combination. This case suggests that stereotactic radiation spares normal tissues and might be safer than conventional fractionated radiation with vemurafenib.
Keywords: VemurafenibStereotactic radiationMelanoma metastasis