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Chordoma in children: Case-report and review of literature
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Abstract
We report an exceptional case of a very late local failure in a 9-year-old boy presenting with a chordoma of the cranio-cervical junction. The child was initially treated with a combination of surgical resection followed by high dose photon–proton radiation therapy. This aggressive therapy allowed a 9-year remission with minimal side-effects. Unfortunately, he subsequently presented with a local failure managed with a second full-dose course of protons. The child died one year later from local bleeding of unclear etiology.
Abstract
We report an exceptional case of a very late local failure in a 9-year-old boy presenting with a chordoma of the cranio-cervical junction. The child was initially treated with a combination of surgical resection followed by high dose photon–proton radiation therapy. This aggressive therapy allowed a 9-year remission with minimal side-effects. Unfortunately, he subsequently presented with a local failure managed with a second full-dose course of protons. The child died one year later from local bleeding of unclear etiology.
Keywords
Chordoma; Sarcoma; Protontherapy; Children
About this articleTitle
Chordoma in children: Case-report and review of literature
Journal
Reports of Practical Oncology and Radiotherapy
Issue
Pages
1-7
Published online
2016-01-01
DOI
10.1016/j.rpor.2015.10.007
Bibliographic record
Rep Pract Oncol Radiother 2016;21(1):1-7.
Keywords
Chordoma
Sarcoma
Protontherapy
Children
Authors
Jean-Louis Habrand
Jean Datchary
Stéphanie Bolle
Anne Beaudré
Ludovic de Marzi
Kévin Beccaria
Dinu Stefan
Jacques Grill
Rémi Dendale