open access

Vol 20, No 6 (2015)
Special Issue Papers
Published online: 2015-11-01
Submitted: 2014-06-04
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Stereotactic radiation therapy for skull base recurrences: Is a salvage approach still possible?

Marco Krengli, Giuseppina Apicella, Letizia Deantonio, Marina Paolini, Laura Masini
DOI: 10.1016/j.rpor.2014.10.007
·
Rep Pract Oncol Radiother 2015;20(6):430-439.

open access

Vol 20, No 6 (2015)
Special Issue Papers
Published online: 2015-11-01
Submitted: 2014-06-04

Abstract

Aim

A literature review was performed to analyse the role of stereotactic radiotherapy given in a single shot or in a fractionated fashion for recurrent skull base tumours in order to ascertain if it can be a real salvage approach.

Background

The management of recurrent skull base tumours can have a curative or palliative intent and mainly includes surgery and RT.

Materials and methods

One-thousand-ninety-one articles were found in the search databases and the most relevant of them were analysed and briefly described.

Results

Data on recurrences of meningioma, pituitary adenoma, craniopharyngioma, chordoma and chondrosarcoma, vestibular schwannoma, glomus jugulare tumours, olfactory neuroblastoma and recurrences from head and neck tumours invading the base of skull are reported highlighting the most relevant results in terms of local control, survival, side effects and complications.

Conclusions

In conclusion, it emerges that SRS and FSRT are effective and safe radiation modalities of realize real salvage treatment for recurrent skull base tumours.

Abstract

Aim

A literature review was performed to analyse the role of stereotactic radiotherapy given in a single shot or in a fractionated fashion for recurrent skull base tumours in order to ascertain if it can be a real salvage approach.

Background

The management of recurrent skull base tumours can have a curative or palliative intent and mainly includes surgery and RT.

Materials and methods

One-thousand-ninety-one articles were found in the search databases and the most relevant of them were analysed and briefly described.

Results

Data on recurrences of meningioma, pituitary adenoma, craniopharyngioma, chordoma and chondrosarcoma, vestibular schwannoma, glomus jugulare tumours, olfactory neuroblastoma and recurrences from head and neck tumours invading the base of skull are reported highlighting the most relevant results in terms of local control, survival, side effects and complications.

Conclusions

In conclusion, it emerges that SRS and FSRT are effective and safe radiation modalities of realize real salvage treatment for recurrent skull base tumours.

Get Citation

Keywords

Skull base; Stereotactic radiotherapy; Tumours; Recurrence; Review

About this article
Title

Stereotactic radiation therapy for skull base recurrences: Is a salvage approach still possible?

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 20, No 6 (2015)

Pages

430-439

Published online

2015-11-01

DOI

10.1016/j.rpor.2014.10.007

Bibliographic record

Rep Pract Oncol Radiother 2015;20(6):430-439.

Keywords

Skull base
Stereotactic radiotherapy
Tumours
Recurrence
Review

Authors

Marco Krengli
Giuseppina Apicella
Letizia Deantonio
Marina Paolini
Laura Masini

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