open access

Vol 20, No 5 (2015)
Original reearch articles
Published online: 2015-09-01
Submitted: 2014-09-01
Get Citation

Dosimetric impact of different multileaf collimators on prostate intensity modulated treatment planning

Lucia Clara Orlandini, Margherita Betti, Christian Fulcheri, Marianna Coppola, Luca Cionini
DOI: 10.1016/j.rpor.2015.06.005
·
Rep Pract Oncol Radiother 2015;20(5):358-364.

open access

Vol 20, No 5 (2015)
Original reearch articles
Published online: 2015-09-01
Submitted: 2014-09-01

Abstract

Aim

The main purpose of this study is to perform a dosimetric comparison on target volumes and organs at risks (OARs) between prostate intensity modulated treatment plans (IMRT) optimized with different multileaf collimators (MLCs).

Background

The use of MLCs with a small leaf width in the IMRT optimization may improve conformity around the tumor target whilst reducing the dose to normal tissues.

Materials and methods

Two linacs mounting MLCs with 5 and 10[[ce:hsp sp="0.25"/]]mm leaf-width, respectively, implemented in Pinnacle3 treatment planning system were used for this work. Nineteen patients with prostate carcinoma undergoing a radiotherapy treatment were enrolled. Treatment planning with different setup arrangements (7 and 5 beams) were performed for each patient and each machine. Dose volume histograms (DVHs) cut-off points were used in the treatment planning comparison.

Results

Comparable planning target volume (PTV) coverage was obtained with 7- and 5-beam configuration (both with 5 and 10[[ce:hsp sp="0.25"/]]mm MLC leaf-width). The comparison of bladder and rectum DVH cut-off points for the 5-beam arrangement shows that 52.6% of the plans optimized with a larger leaf-width did not satisfy at least one of the OARs’ constraints. This percentage is reduced to 10.5% for the smaller leaf-width. If a 7-beam arrangement is used the value of 52.6% decreases to 21.1% while the value of 10.5% remains unchanged.

Conclusion

MLCs collimators with different widths and number of leaves lead to a comparable prostate treatment planning if a proper adjustment is made of the number of gantry angles.

Abstract

Aim

The main purpose of this study is to perform a dosimetric comparison on target volumes and organs at risks (OARs) between prostate intensity modulated treatment plans (IMRT) optimized with different multileaf collimators (MLCs).

Background

The use of MLCs with a small leaf width in the IMRT optimization may improve conformity around the tumor target whilst reducing the dose to normal tissues.

Materials and methods

Two linacs mounting MLCs with 5 and 10[[ce:hsp sp="0.25"/]]mm leaf-width, respectively, implemented in Pinnacle3 treatment planning system were used for this work. Nineteen patients with prostate carcinoma undergoing a radiotherapy treatment were enrolled. Treatment planning with different setup arrangements (7 and 5 beams) were performed for each patient and each machine. Dose volume histograms (DVHs) cut-off points were used in the treatment planning comparison.

Results

Comparable planning target volume (PTV) coverage was obtained with 7- and 5-beam configuration (both with 5 and 10[[ce:hsp sp="0.25"/]]mm MLC leaf-width). The comparison of bladder and rectum DVH cut-off points for the 5-beam arrangement shows that 52.6% of the plans optimized with a larger leaf-width did not satisfy at least one of the OARs’ constraints. This percentage is reduced to 10.5% for the smaller leaf-width. If a 7-beam arrangement is used the value of 52.6% decreases to 21.1% while the value of 10.5% remains unchanged.

Conclusion

MLCs collimators with different widths and number of leaves lead to a comparable prostate treatment planning if a proper adjustment is made of the number of gantry angles.

Get Citation

Keywords

Intensity modulated radiation therapy (IMRT); Multileaf collimator; Prostate treatment

About this article
Title

Dosimetric impact of different multileaf collimators on prostate intensity modulated treatment planning

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 20, No 5 (2015)

Pages

358-364

Published online

2015-09-01

DOI

10.1016/j.rpor.2015.06.005

Bibliographic record

Rep Pract Oncol Radiother 2015;20(5):358-364.

Keywords

Intensity modulated radiation therapy (IMRT)
Multileaf collimator
Prostate treatment

Authors

Lucia Clara Orlandini
Margherita Betti
Christian Fulcheri
Marianna Coppola
Luca Cionini

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk, Poland
tel.:+48 58 320 94 94, fax:+48 58 320 94 60, e-mail: journals@viamedica.pl