Malnutrition and cachexia in patients with head and neck cancer treated with (chemo)radiotherapy

Mojca Gorenc; Nada Rotovnik Kozjek; Primož Strojan

doi:10.1016/j.rpor.2015.03.001

Vol 20, No 4 (2015)

Reviews

Published online: 2015-07-01

Submitted: 2014-12-01

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Malnutrition and cachexia in patients with head and neck cancer treated with (chemo)radiotherapy

Mojca Gorenc, Nada Rotovnik Kozjek, Primož Strojan

DOI: 10.1016/j.rpor.2015.03.001

Rep Pract Oncol Radiother 2015;20(4):249-258.

Vol 20, No 4 (2015)

Reviews

Published online: 2015-07-01

Submitted: 2014-12-01

Abstract

Aim

To highlight the problems associated with nutrition that occur in patients with squamous cell carcinoma of the head and neck (SCCHN).

Background

SCCHN is associated with weight loss before, during and after radiotherapy or concurrent chemoradiotherapy. Because of serious consequences of malnutrition and cachexia on treatment outcome, mortality, morbidity, and quality of life, it is important to identify SCCHN patients with increased risk for the development of malnutrition and cachexia.

Materials and methods

Critical review of the literature.

Results

This review describes pathogenesis, diagnosis and treatment of malnutrition and cancer cachexia. Treatment of malnutrition and cancer cachexia includes nutritional interventions and pharmacological therapy. Advantages and disadvantages of different nutritional interventions and their effect on the nutritional status, quality of life and specific oncological treatment are presented.

Conclusions

Nutritional management is an essential part of care of these patients, including early screening, assessment of nutritional status and appropriate intervention.