open access

Vol 20, No 3 (2015)
Reviews
Published online: 2015-05-01
Submitted: 2013-11-15
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Breast cancer in young women in southern Tunisia: Anatomical study and clinical prognostic factors: About a series of 83 patients

Mouna Kallel, Fatma Elloumi, Abdelmajid Khabir, Lilia Ghorbal, Souhir Chaabouni, Habib Amouri, Mounir Frikha, Jamel Daoud
DOI: 10.1016/j.rpor.2015.01.007
·
Rep Pract Oncol Radiother 2015;20(3):155-160.

open access

Vol 20, No 3 (2015)
Reviews
Published online: 2015-05-01
Submitted: 2013-11-15

Abstract

Purpose

To define epidemiological, clinical, therapeutic and prognostic factors influencing survival of breast cancer in young women younger than 35 in southern Tunisia.

Material and methods

This is a retrospective study of 83 patients younger than 35 years and treated within tumors mammary committee of Sfax.

Results

The mean age was 31.7 years. T2 stage, high grade with positive node tumors were frequent. Breast surgery was performed for 73 patients. Chemotherapy was neo-adjuvant, adjuvant and palliative for respectively 10, 62 and 13 patients. Radiotherapy was delivered for 65 patients with curative intent and for 8 metastatic patients. Endocrine therapy was adjuvant in 38 patients and palliative in 6 cases. The overall survival (OS) at 5 years was 66.8%. Pejorative prognostic factors in uni-variate analysis were clinical T stage (T3, T4), and the number of involved lymph nodes.

Conclusion

Despite adequate treatment, the prognosis of breast cancer in young women remains worse. Early diagnosis is necessary to promote outcome.

Abstract

Purpose

To define epidemiological, clinical, therapeutic and prognostic factors influencing survival of breast cancer in young women younger than 35 in southern Tunisia.

Material and methods

This is a retrospective study of 83 patients younger than 35 years and treated within tumors mammary committee of Sfax.

Results

The mean age was 31.7 years. T2 stage, high grade with positive node tumors were frequent. Breast surgery was performed for 73 patients. Chemotherapy was neo-adjuvant, adjuvant and palliative for respectively 10, 62 and 13 patients. Radiotherapy was delivered for 65 patients with curative intent and for 8 metastatic patients. Endocrine therapy was adjuvant in 38 patients and palliative in 6 cases. The overall survival (OS) at 5 years was 66.8%. Pejorative prognostic factors in uni-variate analysis were clinical T stage (T3, T4), and the number of involved lymph nodes.

Conclusion

Despite adequate treatment, the prognosis of breast cancer in young women remains worse. Early diagnosis is necessary to promote outcome.

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Keywords

Breast; Cancer; Young women; Clinical; Prognosis

About this article
Title

Breast cancer in young women in southern Tunisia: Anatomical study and clinical prognostic factors: About a series of 83 patients

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 20, No 3 (2015)

Pages

155-160

Published online

2015-05-01

DOI

10.1016/j.rpor.2015.01.007

Bibliographic record

Rep Pract Oncol Radiother 2015;20(3):155-160.

Keywords

Breast
Cancer
Young women
Clinical
Prognosis

Authors

Mouna Kallel
Fatma Elloumi
Abdelmajid Khabir
Lilia Ghorbal
Souhir Chaabouni
Habib Amouri
Mounir Frikha
Jamel Daoud

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