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Abstract
The construction of the 68Ge/68Ga generator has increased application of radiopharmaceuticals labeled with this isotope in medicine. 68Ga-PET is widely employed in the management of neuroendocrine tumors but favorable chemistry with tri- and tetraaza-ring molecules has opened wide range of 68Ga application in other fields of PET imaging. This review covers the radiopharmaceuticals labeled with gallium in molecular imaging and shows perspectives on the use of gallium-68 as a substitute for technetium-99, fluorine-18 and carbon-11 in some applications.
Abstract
The construction of the 68Ge/68Ga generator has increased application of radiopharmaceuticals labeled with this isotope in medicine. 68Ga-PET is widely employed in the management of neuroendocrine tumors but favorable chemistry with tri- and tetraaza-ring molecules has opened wide range of 68Ga application in other fields of PET imaging. This review covers the radiopharmaceuticals labeled with gallium in molecular imaging and shows perspectives on the use of gallium-68 as a substitute for technetium-99, fluorine-18 and carbon-11 in some applications.
Keywords
Position emission tomography; [[ce:sup loc=" pre" ]]68Ga labeled compounds; Bifunctional chelators; [[ce:sup loc=" pre" ]]68Gallium-DOTA-peptides
About this articleTitle
Array
Journal
Reports of Practical Oncology and Radiotherapy
Issue
Published online
2014-01-01
DOI
10.1016/j.rpor.2014.04.016
Bibliographic record
Rep Pract Oncol Radiother 2014;19(1).
Keywords
Position emission tomography
[[ce:sup loc="pre"]]68Ga labeled compounds
Bifunctional chelators
[[ce:sup loc="pre"]]68Gallium-DOTA-peptides
Authors
Krzysztof Kilian